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 W. H. Neukom Distinguished Professor of
Computational Sciences
Professor of Psychological and Brain Sciences
Bachelor's, MIT; Ph.D., Yale
Office: (603) 646-9021
richard.granger@dartmouth.edu
Related sites:
Go to: The W.H.Neukom
Institute for Computational Sciences
Go to: The Brain Engineering
Laboratory
Interests
His work includes research in brain circuit analysis, algorithm
development, pharmaceutical development, and robotics. His laboratory includes
a range of undergraduates, graduate students and postdoctoral fellows.
Selected publications
- Granger R (2006) Essential circuits of cognition: The brain's basic
operations, architecture and representations. In: AI at 50: The future of
Artificial Intelligence (J.Moor, G.Cybenko, Eds.) pdf
- Granger R (2006) Engines of the Brain: The computational instruction set of
human cognition. AI Magazine, 27: 15-32. pdf
- Rodriguez, A., Whitson, J., Granger, R. (2005). Derivation and analysis of
basic computational operations of thalamocortical circuits. Journal of
Cognitive Neuroscience, 16: 856-877. pdf
- Granger R. (2004) Brain circuit implementation: High-precision computation
from low-precision components. In: Toward Replacement Parts for the Brain
(T.Berger, D.Glanzman, Eds.) Mass: MIT Press., pp.277-294. pdf
- Granger, R. (2003). Neural Computation: Olfactory cortex as a model for
telencephalic processing. Learning & Memory (J.Byrne, Ed.), pp.445-450. pdf
- Benvenuto, J., Jin, Y., Casale, M., Lynch, G., Granger, R. (2002).
Identification of diagnostic evoked response potential segments in Alzheimer¹s
Disease. Exper. Neurology, 176: 269-276. pdf
- Phillips, D, Sonnenberg, J, Arai, A, Vaswani, R, Krutzik, P, Kleisli, T,
Kessler, M, Granger, R, Lynch, G, Chamberlin, R (2002).
5'-Alkyl-benzothiadiazides: A new subgroup of AMPA receptor modulators with
improved affinity. Bioorganic & Medicinal Chem. 10: 1229-1248. pdf
- Arai, A, Yan-Fang, X, Kessler, M, Phillips, D, Chamberlin, R, Granger, R,
Lynch, G. (2002). Effects of 5'-Alklyl-Benzothiadiazides on AMPA receptor
biophysics and synaptic responses. Molecular Pharmacology, 62: 566-577. pdf
- Shimono, K., Taketani, M., Brucher, F., Kubota, D., Colgin, L., Robertson,
S., Granger R., Lynch, G. (2001). Continuous two-dimensional current-source
density analyses of electrophysiological activity in hippocampal slices.
Neurocomputing 38: 899-905. pdf
- Granger, R. (2001). Method and computer program product for assessing
neurological conditions and treatments using evoked response potentials. U.S.
Patent # 6,223,074 (54 claims).
- Granger, R., and Lynch, G. (2001). Method and apparatus for assessing
susceptibility to stroke. U.S. Patent # 6,280,393 (17 claims).
- Granger, R. (2001). NeuroGraph Evoked Potential System. Food and Drug
Administration (FDA) 510(k) clearance #K010669.
- Shimono, K., Brucher, F., Granger, R., Lynch, G., and Taketani, M. (2000).
Origins and distribution of cholinergically induced beta rhythms in hippocampal
slices. J. Neuroscience 20: 8462-8473. pdf
- Lynch, G., Granger, R., Gall, C., Palmer, L. (2000). Assay for
determination of neuronal activity in brain tissue. U.S. Patent # 5,998,139 (6
claims).
- Lynch, G., and Granger, R. (2000). Method for treating sexual dysfunctions.
U.S. Patent # 6,083,947 (33 claims).
- Davis, M. Ambros-Ingerson, J., Granger, R., Wu, J., Zabaneh, R., Abdelnaby,
M, and Lynch, G. (1998). Triazolam impairs delayed recall but not acquisition
of various everyday memory tasks in humans. Experimental Neurol., 148: 124-134.
pdf
- Kilborn, K., Kubota, D., Lynch, G, and Granger, R. (1998). Parameters of
LTP induction modulate network categorization behavior. In: Computational
Neurosci (NY: Plenum), 353-358.
- Davis, M., Moskovitz, B., Nguyen, M., Lynch, G., Rogers, G., Granger, R.
(1997). A profile of the behavioral changes produced by facilitation of
AMPA-type glutamate receptors. Psychopharmacology, 133: 161-167.
- Garzotto, A., Aleksandrovsky, B., Lynch, G., Granger, R. (1997). A
neocortically derived model of continuous contextual processing. IEEE Press,
Proc. Int¹l Conf Neural Networks, 1: 564-568.
- 16. Aleksandrovsky, B., Brucher, F., Lynch, G., Granger, R. (1997). Neural
network model of striatal complex. In: Biological and Artificial Computation:
From Neuroscience to Technology. Int¹l Conf on Artificial and Natural Neural
Networks, Berlin: Springer-Verlag, pp.104-115.
- Hess, U.S., Granger, R., Lynch, G., Gall, C.M. (1997). Differential
patterns of c-fos mRNA expression in amygdala during successive stages of odor
discrimination learning. Learning and Memory, 4: 262-283.
- Lynch, G., Granger, R., Davis, M., Ambros-Ingerson, J., Kessler, M.,
Schehr, R. (1997). Evidence that a positive modulator of glutamate receptors
improves recall in elderly human subjects. Experimental Neurol., 145:
89-92.
- Ingvar, M., Ambros-Ingerson, J., Davis, M., Granger, R., Kessler, M.,
Rogers, G, Schehr, R., and Lynch., G. (1997). Enhancement by an ampakine of
memory encoding in humans. Exper. Neurol., 146: 553-559. pdf
- Granger, R., Wiebe, S., Taketani, M., Ambros-Ingerson, J., Lynch, G.
(1996). Distinct memory circuits comprising the hippocampal region.
Hippocampus, 6: 567-578. pdf
- Kilborn, K., Lynch, G., and Granger, R. (1996). Effects of LTP on response
selectivity of simulated cortical neurons. J. Cog. Neurosci., 8: 328-343. pdf
- Aleksandrovsky, B., Whitson, J., Andes, G., Lynch, G., Granger, R. (1996).
Novel speech processing mechanism derived from auditory neocortical circuit
analysis. IEEE Press, Proc. ICSLP Int¹l Conf. on Spoken Language, 1:
558-561.
- Lynch, G., Kessler, M., Rogers, G., Ambros-Ingerson, J., Granger, R. and
Schehr, R. (1996). Psychological effects of a drug that facilitates brain AMPA
receptors. Int J Clinical Psychopharmacol, 11: 13-19.
- Granger, R., Deadwyler, S., Davis, M., Moskowitz, B., Kessler, M., Rogers,
G., and Lynch, G. (1996). Facilitation of glutamate receptors reverses an
age-associated memory impairment in rats. Synapse, 22: 332-337.
- Aleksandrovsky, B., Whitson, J., Garzotto, A, Lynch, G., Granger, R.
(1996). An algorithm derived from thalamocortical circuitry stores and
retrieves temporal sequences. IEEE Comp.Soc.Press, Proc. Int¹l Conf. Pattern
Recog., 4: 550-554.
- Myers, C., Gluck, M., and Granger, R. (1995). Dissociation of hippocampal
and entorhinal function in associative learning: A computational approach.
Psychobiology, 23: 116-138.
- Ozeki, T., Shouval, H., Intrator, N. and Granger, R. (1995). Analysis of a
temporal sequence learning network based on the property of LTP induction. In:
Int'l Symposium on Nonlinear Theory, Las Vegas.
- Granger, R. and Lynch, G. (1994). Cognitive modularity: Computational
division of labor in the brain. In: The Handbook of Neuropsychology, New York:
Academic Press. 9: 263-277.
- Kowtha, V., Satyanarayana, P., Granger, R., and Stenger, D. (1994).
Learning and classification in a noisy environment by a simulated cortical
network. Proc. Third Ann. Comp. & Neural Systems Conf., Boston: Kluwer, pp.
245-250.
- Coultrip, R. and Granger, R. (1994). LTP learning rules in sparse networks
approximate Bayes classifiers via Parzen's method. Neural Networks, 7:
463-476.
- Granger, R., Whitson, J., Larson, J. and Lynch, G. (1994). Non-Hebbian
properties of LTP enable high-capacity encoding of temporal sequences. Proc.
Nat'l. Acad. Sci., 91: 10104-10108.
- Gluck, M. and Granger, R. (1993). Computational models of the neural bases
of learning and memory. Ann. Rev. Neurosci. 16: 667-706.
- Granger, R., Staubli, U., Davis, M., Perez, Y., Nilsson, L., Rogers, G.,
and Lynch, G. (1993). A drug that facilitates glutamatergic transmission
reduces exploratory activity and improves performance in a learning-dependent
task. Synapse, 15: 326-329.
- Anton, P., Granger, R., and Lynch, G. (1993). Simulated dendritic spines
influence reciprocal synaptic strengths and lateral inhibition in the olfactory
bulb. Brain Res., 628: 157-165.
- Anton, P., Granger, R. and Lynch, G. (1992). Temporal information
processing in synapses, cells and circuits. In: Single neuron computation,
(McKenna, Davis and Zornetzer, Eds.), NY: Academic Press, 291-313.
- Coultrip, R., Granger, R., and Lynch, G. (1992). A cortical model of
winner-take-all competition via lateral inhibition. Neural Networks, 5:
47-54.
- Lynch, G. and Granger, R. (1992). Variations in synaptic plasticity and
types of memory in cortico-hippocampal networks. J. Cog. Neurosci., 4:
189-199.
- Anton, P., Lynch, G., and Granger, R. (1991). Computation of
frequency-to-spatial transform by olfactory bulb glomeruli. Biol. Cybern., 65:
407-414.
- Granger, R., and Lynch, G. (1991). Higher olfactory processes: Perceptual
learning and memory. Current Opin. Neurosci., 1: 209-214.
- Granger, R., Staubli, U., Powers, H., Otto, T., Ambros-Ingerson, J., and
Lynch, G. (1991). Behavioral tests of a prediction from a cortical network
simulation. Psychol. Sci., 2: 116-118.
- McCollum, J., Larson, J., Otto, T., Schottler, F. Granger, R., and Lynch,
G. (1991). Short-latency single-unit processing in olfactory cortex. J. Cog.
Neurosci., 3: 293-299.
- Lynch, G., Larson, J., Staubli, U., Ambros, J., and Granger, R. (1991).
Long-term potentiation and memory operations in cortical networks. In
Perspectives on Cognitive Neuroscience, Lister, R., and Weingartner, H. (Eds.),
New York: Oxford Univ. Press, 110-131.
- Granger, R., Staubli, U., Ambros-Ingerson, J., and Lynch, G. (1991).
Specific behavioral predictions from simulations of the olfactory system. In:
Olfaction as a model system for computational neuroscience, (H.Eichenbaum and
J.Davis, Eds.), Cambridge: MIT Press.
- Lynch, G., Granger, R., and Larson, J. (1990). Empirically derived synaptic
learning rules and the phenomenology of memory. FESN Discussions in
Neuroscience, 6: 85-89.
- Lynch, G. and Granger, R. (1990). Olfactory rhythms and the encoding of
memory. Proc. 10th Internat. Symp. on Olfaction and Taste, Oslo, Norway,
246-264.
- Ambros-Ingerson, J., Granger, R., and Lynch, G. (1990). Simulation of
paleocortex performs hierarchical clustering. Science, 247: 1344-1348.
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