Federal Limited Opportunities

Collaborative Program Grant for Multidisciplinary Teams (RM1 - Clinical Trial Optional)

NIGMS

This Funding Opportunity Announcement (FOA) is designed to support highly integrated research teams of three to six Program Directors/Principal Investigators (PDs/PIs) to address ambitious and challenging research questions that are within the mission of NIGMS. Project goals should not be achievable with a collection of individual efforts or projects. Collaborative program teams are expected to accomplish goals that require considerable synergy and managed team interactions. Teams are encouraged to consider far-reaching objectives that will produce major advances in their fields.

This FOA is not intended for applications that are mainly focused on the creation, expansion, and/or maintenance of community resources, creation of new technologies, or infrastructure development.

NIGMS will accept TWO applications per institution. 

To apply for this opportunity email the following to limitedfunding@dartmouth.edu:

Overview/abstract of proposal (one page maximum)
Total request amount
Curriculum Vitae (CV)

Internal Deadline: April 10, 2026
Sponsor Deadline: May 27, 2026

National Institute of General Medical Sciences Predoctoral Basic Biomedical Sciences Research Training Program (T32)

National Institute of General Medical Sciences (NIGMS)

The goal of the National Institute of General Medical Sciences (NIGMS) Ruth L. Kirschstein National Research Service Award (NRSA) Predoctoral Basic Biomedical Sciences Research Training Program is to develop a diverse pool of well-trained scientists available to address the nation’s biomedical research agenda. Specifically, this funding announcement provides support to eligible, domestic organizations to develop and implement effective, evidence-informed approaches to biomedical graduate training and mentoring that will keep pace with the rapid evolution of the biomedical research enterprise. NIGMS expects that the proposed research training programs will incorporate didactic, research, and career development elements to prepare trainees for careers that will have a significant impact on the health-related research needs of the nation. 

LIMIT: Applicant organizations may submit more than one application, provided that each application is distinct with respect to the scientific area of research training. Through this funding announcement, NIGMS will accept predoctoral training grant applications to enhance graduate research training in 12 broad areas of basic biomedical sciences. NIGMS will support only one training program in a basic biomedical science research training area per applicant organization (normally identified by having a Unique Entity Identifier (UEI) and a unique NIH eRA Institutional Profile File (IPF) number).

To apply for this opportunity, email the following to limitedfunding@dartmouth.edu

Overview/abstract of proposal (one page maximum)
Total request amount
Leadership Biosketches 

Applicants must identify one of the eleven(11) areas listed below under which the proposal will be submitted.

1 BBS: Behavioral-Biomedical Sciences Interface * No Longer Available*
2 BS: Biostatistics
3 BT: Biotechnology
4 CBM: Cellular, Biochemical, and Molecular Sciences
5 CBI: Chemistry-Biology Interface
6 CBB: Computational Biology, Bioinformatics, and Biomedical Data Science
7 GEN: Genetics
8 MB: Molecular Biophysics
9 MM: Molecular Medicine
10 PS: Pharmacological Sciences
11 SIB: Systems and Integrative Biology

Internal Deadline: April 25, 2026 

Sponsor Deadline: September 25, 2026

NSF 24-573 EPSCoR Research Infrastructure Improvement Program: Focused EPSCoR Collaborations Program

Program Description

The primary driver for FEC investments is the need to build STEM-driven, inter-jurisdictional research collaborations with the potential to be nationally and internationally competitive. The Project Description should include a strong rationale for the collaboration and demonstrate that the partnership is designed to facilitate discovery and innovation in the focus area (detailed in the published biennial Dear Colleague Letter), which neither party could address as well, or as rapidly, alone. FEC projects are unique in their integration of researchers into collaborative teams across EPSCoR jurisdictions, and must develop a well-prepared, STEM-enabled workforce necessary to sustain research competitiveness.

For NSF EPSCoR to achieve this vision, requires not only advancing the frontiers of science, engineering, and education but also ensuring that U.S. research is an inclusive enterprise that harnesses the talent of all sectors of American society.

Therefore, the recruitment and/or development of early-career faculty, postdoctoral researchers, undergraduates, graduate students, and K-12 students, are critical in achieving this goal and must be an integral component of the proposed project.

Over the long term, RII-FEC investments are expected to result in sustained improvements in research competitiveness, enabling EPSCoR investigators to successfully pursue significant opportunities of national and international importance in science and engineering research and education. It is expected that previous NSF and other federal agency investments will be leveraged and translated into advancing the understanding of the focus area. All proposals must clearly indicate the intended social impact, demonstrating how the project will benefit the community in the involved jurisdiction(s). Non-EPSCoR and international collaborations may be included, but no EPSCoR funds should be directed to these organizations

Central to the success of the proposal is a clear demonstration that the collaboration is well-positioned to produce outcomes that cannot be obtained through the efforts of a team in a single jurisdiction working alone. The proposal must clearly identify the roles and contributions of each partner in the project, the anticipated increases in research capacity and competitiveness, the projected workforce development and educational plan and outcomes, and the benefits to the jurisdictions, the Nation, and society. It is expected that these collaborations be balanced, with participating jurisdictions each contributing to and benefiting from projects at levels that are appropriate to their capabilities.

To ensure maximum impact of available programmatic funds, requests for RII-FEC funding must:

• Add significantly to the research capacity of the participating jurisdictions in the focus area;
• Contribute to the advancement of research and innovation in the focus area;
• Illustrate how the participating jurisdictions' research capacities will be positively impacted by the collaborative effort;
• Outline clear plans for the recruitment and/or development of the full spectrum of diverse talent in STEM as early-career faculty;
• Engage the full diversity of the participating jurisdictions' resources including two- and four-year colleges, Minority-Serving Institutions, and local and state industries in STEM workforce development;
• Include social and economic expertise to understand and assess the societal implications of the focus area, as detailed in the published biennial Dear Colleague Letter (DCL); and
• Present a sustainability plan for obtaining subsequent, sustained non-EPSCoR funding from federal, jurisdictional, or private sector sources.

RII-FEC proposals are expected to be STEM-driven collaborations and the PI and co-PIs should all be active researchers in the research topic(s) of the proposal. Proposals should clearly explain how the proposed research, education, and workforce development activities will create or increase the capacity for the jurisdictions involved to participate in continued research. Proposals must include a timetable or strategic plan for achieving those goals, and/or a logic model with a clearly articulated theory of change that identifies appropriate indicators of progress towards the desired outcomes.

 To apply for this opportunity email the following to limitedfunding@dartmouth.edu

Overview/abstract of proposal (one page maximum)
Total request amount
Curriculum Vitae (CV) or biosketch

Internal Deadline: June 25, 2026
Sponsor Letter of Intent (LOI) required Deadline: December 15, 2026 (requires OSP review and submission)

Sponsor Application Deadline: January 26, 2027

Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)

NIH

Through the Seed Instrumentation Support (SIS) Program, NIH supports the purchase of a single commercialized research instrument that is currently unavailable to the applicant institutions. Like a seed, the instruments are expected to help promote new research opportunities, expand existing research capabilities, foster collaboration and training, and support the growth of future research activities.

Modern research instruments are essential for generating high quality and reproducible data that drive innovations in biomedical and biobehavioral research in all institutions, including low-resource ones. Instruments funded through this program will be shared among users to promote cost-effective research for reproducible biomedical data generation. Hence, the instrument is expected to be placed in a safe and accessible shared resource to maximize collaboration. This NOFO encourages different outcomes based on institutional type: (i) For research-intensive institutions, emphasis is placed on acquiring new or emerging technologies that enable innovative and novel research; and (ii) For low-resource institutions (e.g., R15-eligible institutions that have not received more than $6 million per year in NIH funding in 4 of the last 7 federal fiscal years), the focus is on building foundational research capacity, expanding the biomedical research workforce, and supporting sustainable, long-term research programs. Institutions applying under this category will clearly justify their low-resource status in the application.

Eligible instruments include, but are not limited to, mass spectrometers, cell sorters, bioimagers, DNA and protein sequencers, light microscopes, 3D printers, and high-performance computers. Applications for general purpose computer systems (computer clusters and data storage systems) will only be considered if the system is solely dedicated to biomedical research.

Foreign-made instruments are allowed. However, the reasons for choosing foreign-made instruments over domestically manufactured instruments will be justified. NIH urges that every effort should be made to give preference to domestically manufactured instruments to the maximum extent possible. Additionally, requesting funds towards purchasing an instrument under a lease agreement is strongly discouraged.

Applications will be accepted that request a single, commercially available instrument. The minimum award is $50,000. There is no upper limit on the cost of the instrument, but the maximum award is $400,000. 

Applicant organizations may submit only one application, provided that the type of instrument does not currently exist in the applicant organization (identified by UEI).

To apply for this opportunity email the following to limitedfunding@dartmouth.edu:

Overview/abstract of proposal (one page maximum)
Total request amount
Curriculum Vitae (CV)

Internal Deadline: August 7, 2026
Sponsor Deadline: September 25, 2026