Michael L. Whitfield, PhD
Assistant Professor, Genetics
Email:michael.whitfield@dartmouth.edu
Education:
1999 - 2003 Stanford University School of Medicine Post-doctoral Fellow, Genetics
1994 - 1999 University of North Carolina, Chapel Hill Ph.D., Biochemistry and Biophysics
1990 - 1994 North Carolina State University, Raleigh B.S. Biochemistry / B.A. Chemistry,
Magna Cum Laude
Publications:
1. Whitfield,M.L., Handan Kaygun, Judith A. Erkmann, W.H. Davin Townley-Tilson, Zbigniew Dominski, and William F. Marzluff. SLBP is associated with histone mRNA on polyribosomes as a component of the histone mRNP. Nuc. Acids Res. (2004) Vol. 32, No. 16: 4833-4842. Web - Abstract - PDF - Supplement
2. Novoradovskaya, N., Michael L. Whitfield, Lee S. Basehore, Alexey Novoradovsky, Robert Pesich, Jerry Usary, Mehmet Karaca, Winston Wong, Olga Aprelikova, Michael Fero, Charles M. Perou, David Botstein, Jeff Braman. Universal Reference RNA as a standard for microarray experiments. BMC Genomics. (2004) Mar 09;5(1):20. Web - Abstract - PDF
3. Murray, J.I., Michael L. Whitfield, Nathan D. Trinklein, Richard M. Myers, Patrick O. Brown, David Botstein. Diverse and specific gene expression responses to stresses in cultured human cells. Mol Biol Cell. (2004) May;15(5):2361-74. Epub 2004 Mar 05. Web - Abstract - PDF - Supplement
4. Zhao, H., Michael L. Whitfield, Tong Xu, David Botstein, James D. Brooks. Diverse effects of methylseleninic acid on the transcriptional program of human prostate cancer cells. (2004) Mol Biol Cell 15: 506-519. Web - Abstract - PDF - Supplement
5. Whitfield,M.L., Finlay,D., Murray,J.I., A.Troyanskaya,O., Chi,J.A., Brown,P.O., Botstein,D. and Connolly,M.K. Systemic and cell-type specific manifestations in the gene expression patterns in scleroderma skin. (2003) PNAS 100(21) pg 12319-12324 Abstract - PDF - Supplement
6. Whitfield,M.L., Gavin Sherlock, Alok Saldanha, John I. Murray, Catherine A. Ball, Karen E. Alexander, John C. Matese, Charles M. Perou, Myra M. Hurt, Patrick O. Brown and David Botstein (2002) Identification of Genes Periodically Expressed in the Human Cell Cycle and Their Expression in Tumors. Mol. Biol. Cell, 13, 1977 - 2000. Link - Abstract - PDF - Supplement
7. Zhao, H., Trevor Hastie, Michael L. Whitfield, Anne-Lise Borresen-Dale and Stefanie S. Jeffrey (2002). Optimization and evaluation of T7 based RNA linear amplification protocols for cDNA microarray analysis. BMC Genomics, 3: 31 Link - Abstract
8. Allard,P., Marc J. Champigny, Sarah Skoggard, Judith A. Erkmann, Michael L. Whitfield, William F. Marzluff and Hugh J. Clarke (2002) Stem-loop Binding Protein Accumulates During Oocyte Maturation and is Not Cell Cycle-Regulated in the Early Mouse Embryo. J. Cell Sci. 115, 4577 - 4586. Web
9. Whitfield,M.L., Lian-Xing Zheng, Amy Baldwin, Tomohiko Ohta, Myra M. Hurt, and William F. Marzluff (2000). Stem-loop binding protein, the protein that binds the 3' end of histone mRNA, is cell cycle regulated by both translational and posttranslational mechanisms. Mol. Cell Biol. 20, 4188-4198. Web - PDF
10. Richardson,R.T., Iglika N. Batova, Esther E. Widgren, Lian-Xing Zheng, Michael Whitfield, William F. Marzluff and Michael G. O'Rand (2000). Characterization of the histone H1 binding protein, NASP, as a cell cycle regulated, somatic protein. J. Biol. Chem. 275, 30378-30386. Web - PDF
11. Wang,Z.F., Michael L. Whitfield, Thomas C. Ingledue, III, Zbigniew Dominski and William F. Marzluff (1996). The protein that binds the 3' end of histone mRNA: a novel RNA-binding protein required for histone pre-mRNA processing. Genes Dev. 10, 3028-3040. Abstract
Whitfield Laboratory
Dartmouth Medical School
Department of Genetics
Remsen 705
Hanover, NH 03755
Phone: 603-650-1105
Fax: 603-650-1188