Selected Publications

Rollenhagen C, Wöllert T, Langford GM, Sundstrom P. Stimulation of cell motility and expression of late markers of differentiation in human oral keratinocytes by Candida albicans. Cell Microbiol. 11(6):946-66, 2009.

Bahn YS, Molenda M, Staab JF, Lyman CA, Gordon LJ, Sundstrom P. Genome-wide transcriptional profiling of the cyclic AMP-dependent signaling pathway during morphogenic transitions of Candida albicans. Eukaryot Cell. 6(12):2376-90, 2007.

Wolyniak MJ, Sundstrom P. Role of actin cytoskeletal dynamics in activation of the cyclic AMP pathway and HWP1 gene expression in Candida albicans. Eukaryot Cell. 6(10):1824-40, 2007.

Ponniah G, Rollenhagen C, Bahn YS, Staab JF, Sundstrom P. State of differentiation defines buccal epithelial cell affinity for cross-linking to Candida albicans Hwp1. J Oral Pathol Med. 36(8):456-67, 2007.

Kim S, Wolyniak MJ, Staab JF, Sundstrom P. A 368-base-pair cis-acting HWP1 promoter region, HCR, of Candida albicans confers hypha-specific gene regulation and binds architectural transcription factors Nhp6 and Gcf1p. Eukaryot Cell. 6(4):693-709, 2007.

Naglik JR, Fostira F, Ruprai J, Staab JF, Challacombe SJ, Sundstrom P. Candida albicans HWP1 gene expression and host antibody responses in colonization and disease. J Med Microbiol. (Pt 10):1323-7, 2006.

Staab JF, Bahn YS, Tai CH, Cook PF, Sundstrom P. Expression of transglutaminase substrate activity on Candida albicans germ tubes through a coiled, disulfide-bonded N-terminal domain of Hwp1 requires C-terminal glycosylphosphatidylinositol modification. J Biol Chem. 279(39):40737-47, 2004.

Bahn YS, Staab J, Sundstrom P. Increased high-affinity phosphodiesterase PDE2 gene expression in germ tubes counteracts CAP1-dependent synthesis of cyclic AMP, limits hypha production and promotes virulence of Candida albicans. Mol Microbiol. 50(2):391-409, 2003.

Daniels KJ, Lockhart SR, Staab JF, Sundstrom P, Soll DR.The adhesin Hwp1 and the first daughter cell localize to the a/a portion of the conjugation bridge during Candida albicans mating. Mol Biol Cell. 14(12):4920-30, 2003.

Staab JF, Bahn YS, Sundstrom P. Integrative, multifunctional plasmids for hypha-specific or constitutive expression of green fluorescent protein in Candida albicans. Microbiology. 149(Pt 10):2977-86, 2003.

Staab JF, Sundstrom P. URA3 as a selectable marker for disruption and virulence assessment of Candida albicans genes. Trends Microbiol. 11(2):69-73. Review, 2003.

Sundstrom P. Adhesion in Candida spp. Cell Microbiol. 4(8):461-9. Review, 2002.

Sundstrom P, Cutler JE, Staab JF. Reevaluation of the role of HWP1 in systemic candidiasis by use of Candida albicans strains with selectable marker URA3 targeted to the ENO1 locus. Infect Immun. 70(6):3281-3, 2002.

Haberland-Carrodeguas C, Allen CM, Beck FM, Buesching WJ, Koletar SL, Sundstrom P. Prevalence of fluconazole-resistant strains of Candida albicans in otherwise healthy outpatients. J Oral Pathol Med. 31(2):99-105, 2002.

Sundstrom P, Balish E, Allen CM. Essential role of the Candida albicans transglutaminase substrate, hyphal wall protein 1, in lethal oroesophageal candidiasis in immunodeficient mice. J Infect Dis. 185(4):521-30, 2002.

Bahn YS, Sundstrom P. CAP1, an adenylate cyclase-associated protein gene, regulates bud-hypha transitions, filamentous growth, and cyclic AMP levels and is required for virulence of Candida albicans. J Bacteriol. 183(10):3211-23, 2001.

Sundstrom P. Adhesins in Candida albicans. Curr Opin Microbiol. 2(4):353-7. Review, 1999.

Staab JF, Bradway SD, Fidel PL, Sundstrom P. Adhesive and mammalian transglutaminase substrate properties of Candida albicans Hwp1. Science. 283(5407):1535-8, 1999.

Staab JF, Sundstrom P. Genetic organization and sequence analysis of the hypha-specific cell wall protein gene HWP1 of Candida albicans. Yeast. 1998 May;14(7):681-6.

Staab JF, Ferrer CA, Sundstrom P. Developmental expression of a tandemly repeated, proline-and glutamine-rich amino acid motif on hyphal surfaces on Candida albicans. J Biol Chem. 271(11):6298-305, 1996.