Christopher Stroupe, Ph.D.

 

Laboratory Address

Department of Biochemistry

Dartmouth Medical School

7200 Vail, Room 425 Remsen

Hanover, NH 03755

(603) 650-1702

 

Postdoctoral experience

 

2001 - present        Postdoctoral associate, Wickner laboratory, Department of Biochemistry, Dartmouth Medical School

 

Education

 

1994 - 2000              Yale University

                                 Ph.D., Molecular Biophysics and Biochemistry

                                 Thesis advisor: Axel T. Brunger

                                 Thesis project: Crystal structures of Sec4 bound to GDP and to a nonhydrolyzable GTP analog

 

1990 - 1994              Massachusetts Institute of Technology

                                 S.B., Biology

                                 Undergraduate advisor: Boris Magasanik

 

Teaching experience

 

1997, 1999               Yale University, Department of Molecular Biophysics and Biochemistry. Teaching assistant, Principles of Biochemistry I

 

1996                         Yale University, Department of Molecular Biophysics and Biochemistry. Teaching assistant, Laboratory for Biochemistry

 

Academic Honors

 

NIH postdoctoral fellow, 2002 - 2005

Howard Hughes Medical Institute predoctoral fellow, 1994 - 1999

Phi Beta Kappa

 

Society Memberships

 

American Society for Cell Biology, 2003 - present

Sigma Xi Scientific Research Society, 1994 - present

 

Publications

 

Christopher Stroupe, Kevin M. Collins, Rutilio A. Fratti, and William T. Wickner. (2006) Purification of active HOPS complex reveals its affinities for phosphoinositides and the SNARE Vam7p. EMBO Journal 25: 1579-89 (evaluated by Faculty of 1000 Biology, 19 April 2006) PubMed PDF

 

Christopher Stroupe and Axel T. Brunger. (2000) Crystal structures of a Rab protein in its inactive and active conformations. Journal of Molecular Biology 304: 585-598 PubMed PDF

 

Nobuyuki Ota, Christopher Stroupe, J.M.S. Ferreira-da-Silva, Sapan A. Shah, Marcos Mares-Guia, and Axel T. Brunger. (1999) Non-Boltzmann thermodynamic integration (NBTI) for macromolecular systems: Relative free energy of binding of trypsin to benzamidine and benzylamine. Proteins: Structure, Function, and Genetics 37: 641-653 PubMed PDF