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Chair: Hermes H. Yeh
Professors D. Bartlett Jr., R. A. Darnall (Pediatrics and Physiology),
J. A. Daubenspeck (Physiology and Biomedical Engineering), G. Fejes-Toth, V. A.
Galton, P. M. Guyre, L. P. Henderson (Physiology and Biochemistry), J. C.
Leiter (Physiology and Medicine), H. L. Manning (Medicine and Physiology), R.
A. Maue (Physiology and Biochemistry), A. Naray-Fejes-Toth, E. E. Nattie, W. G.
North, D. L. St. Germain (Medicine and Physiology), W. M. St. John, B. A.
Stanton, H. M. Swartz (Radiology, Physiology and Community and Family
Medicine), C. R. Wira, H. H. Yeh; Visiting Professor A. Katz (Medicine and
Physiology); Associate Professors R. B. Robey, P. M. Simon (Medicine and
Physiology); Assistant Professor E. deMuinck (Medicine and Physiology);
Research Associate Professors J. E. Bodwell, A. L. Givan; Research Assistant
Professors J.V. Fahey, A. Li, M. Niblock, P. A. Pioli, M. J. Schneider, L. A.
Sheldon, A. Swiatecka-Urban.
The Physiology Graduate Program is centered in the Physiology Department of
Dartmouth Medical School, which is located in the Borwell Building at the
Dartmouth-Hitchcock Medical Center. It includes faculty from other departments
in the Medical School. The courses listed below are designed for graduate
students.
REQUIREMENTS FOR THE DOCTOR'S DEGREE (PH.D.)
To qualify for award of the Ph.D. degree, a student must fulfill the
following requirements:
1. The Medical Physiology courses (Physiology 110 and 120) plus an
additional section in Gastro-Intestinal Physiology.
2. Two terms of Biochemistry.
3. The Medical Neuroscience course.
4. The Critical Reading of Scientific Literature course.
5. A course on Scientific Ethics.
6. Three research rotations.
7. The Comprehensive Examination.
8. Two Advanced Physiology courses.
9. Two elective courses, which may be either a core course or an advanced
course offered by either Physiology or another department.
10. Thesis research propositional examination.
11. Laboratory research leading to the preparation of a thesis.
12. Defense of the thesis.
COURSES OFFERED
110, 120. Medical Physiology
Fall 2006 (110), Winter 2007 (120)
The human organism is approached by an introduction to general principles,
the properties of living cells, and a description of organ systems and their
characteristics. Emphasis is placed upon mechanisms of integration and
control.
Physiology 110 (58 hours) deals with cardiovascular and respiratory
mechanisms; Physiology 120 (58 hours) deals with renal and endocrine
physiology. Both courses are required of all medical students and MCSP graduate
students. The staff.
Graduate or Elective Courses. One or more of the following courses
is offered each academic year. In addition, special topics requested by
students and/or of timely importance may be offered. Students may also elect to
take courses given by other departments.
114. Advanced Respiratory Physiology
(The staff). Spring 2007, every 4th year
115. Advanced Endocrine Physiology
(The staff). Fall 2007, every 4th year
116. Advanced Cardiovascular Physiology
(The staff). Spring 2009, every 4th year
117. Advanced Renal Physiology
(The staff). Fall 2009, every 4th year
118. Advanced Neurophysiology
(The staff). As requested
119. Advanced Immunology: Mucosal Immunity
(The staff). As requested
124. Ethical Conduct of Research (Identical to Pharmacology
124)
(The staff). Fall 2006, offered every year
This course is required for all MCSP graduate students. There are
approximately seven one-hour lecture/discussion sessions with the times to be
arranged. Topics include: scientific freedom, ethical treatment of data,
ethical use of laboratory animals, priority of discovery, fraud and deception,
and science and the political process.
Faculty lectures and discussion. Prerequisite: none. Instructors: North,
Green, Ermeling, Hoopes, Wray, and others.
125. Critical Reading of Scientific Literature
Spring annually
Critical reading of scientific literature is a skill that can be learned.
This course exposes students to readings from the physiological literature with
the guidance of faculty members who will assist the students in discriminating
good from bad scientific presentation. Readings from various areas of
physiology will be considered and discussed. This course will be given during
the Spring term and is required for first-year physiology graduate students.
Course director: Daubenspeck.
128. Perinatal Physiology
(Darnall). As requested
129. Advanced Comparative Physiology
(Leiter). As requested
132. Physiological Systems Modeling
(Daubenspeck). Summer 2007, every 2nd year
Ordinary, time-varying, nonlinear differential equations describe a wide
range of physiological systems and responses. Students will learn to model
dynamic physiological systems including excitable membrane phenomena,
cardiovascular and respiratory system mechanics and control, and other systems
of particular interest to each student. The orientation of the course is
pragmatic rather than theoretical, and the goal of the course is to teach
students how to construct and evaluate quantitative simulations of
physiological phenomena using commonly available computer tools. There are no
prerequisites for this course beyond successful completion of the first-year
Physiology course. This course will be offered in alternate Spring terms, next
in 2007, and will meet at the convenience of the participants.
QUALIFYING EXAMINATIONS
136. Comprehensive Examination
This is an
open-book, written examination for graduate students, taken in June after the
completion of the course in Medical Physiology. Students are given two weeks in
which to take the test.
138. Thesis Propositional Examination
The propositional
examination will consist of two parts, both based on the thesis research
proposal: (i) preparation and oral defense of the proposal written as a
predoctoral fellowship application; (ii) submission of the application, if
appropriate, to a funding agency.
140-145. Research Rotations in Physiology (one course credit)
Three of the
following rotations are required, each consisting of an association with a
different laboratory for up to six months. During each rotation an original
research project will be carried out, requiring at least half time for 10
weeks. The results of the research must be formally written up, and usually
they are also presented orally as part of Physiology 135. The staff.
140. Research Rotation in Cardiovascular Physiology
141. Research Rotation in Endocrine Physiology
142. Research Rotation in Neurophysiology
143. Research Rotation in Renal Physiology
144. Research Rotation in Respiratory Physiology
145. Research Rotation in Special Topics
146. Research Rotation in Immunology
150. Neurosciences I (Henderson/Maue)
As requested
This course is designed for students with a solid fundamental background in
Neuroscience. Students should have completed Medical Neuroscience or the
equivalent as a prerequisite. Students without this background who wish to take
this course may do so with permission of the Instructor. Lectures will cover
both classical papers relevant to cellular and molecular neuroscience as well
as recent studies that highlight controversial and important findings in this
field. Students will be required to read and critique original research papers.
Discussion of these papers is an integral part of the course.
Physiology graduate students registering for advanced elective credit should
register for Physiology 118. Henderson.
155. Individual Tutorial on Topics in Physiology (offered as
requested)
160-165. Same as 140-145, but two course credits.
297. Thesis Research in Physiology (one course credit)
298. Thesis Research in Physiology (two course credits)
299. Thesis Research in Physiology (three course credits)
Original
laboratory research leading to the preparation of a thesis of publishable
quality, which must be defended before an examining committee consisting of
five members, including at least two from other departments. The staff.
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