Our QBS students come for a wide variety of backgrounds, with a wide variety of research interests and professional goals.
Awards, Abstracts, and Poster Presentations
- NIH-Dartmouth Big Data to Knowledge (BD2K) Fellow
- Titus AJ*, Houseman EA*, Johnson KC, Christensen BC (2016) methyLiftover: cross-platform DNA methylation data integration. Bioinformatics. 32(16):2517-9. *co-first
- Titus AJ, Faill R, Das AK (In Press) Automatic identification of co-occurring patient events. Proceedings of the 7th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics. 579-86.
- Titus AJ, Faill R, Das AK (2016) Automatic identification of co-occurring patient events. Workshop on Methods and Applications in Healthcare Analytics. 7th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics. ACM, Seattle, WA, USA. Oral Presentation.
- Titus AJ, Houseman EA, Johnson KC, Christensen BC (2016) methyLiftover: cross-platform DNA methylation data integration. Computational Life Sciences Workshop @ Bayer. Berlin, Germany. Poster
Awards, Abstracts, and Poster Presentations
- Dartmouth Graduate Studies Graduate Alumni Research Award
- Cystic Fibrosis Foundation Student Traineeship
- Recent Publications
See QBS Graduates
Thesis title: Statistical methods for gene set annotation optimization, unsupervised gene set testing and independent gene set filtering.
Current position: Instructor in Biomedical Data Science, Division of Biostatistics, Geisel School of Medicine at Dartmouth
Research interests: Biomedical informatics, biostatistics, applied mathematics
Thesis Title: Prenatal and childhood exposure to low-level arsenic in the US population
Current Position: Assistant Professor Department of Systems, Populations and Leadership at University of Michigan
Dr. Davis is a quantitatively-oriented health services researcher who has additional training in health informatics, epidemiology, and statistics. He is motivated by questions related to healthcare delivery and he uses rigorous methods to study important policy-relevant issues.
Dr. Davis's research has received national media attention. Articles about his research have appeared in outlets such as Forbes, The Huffington Post, USA Today, Time, The Atlantic, and Consumer Reports. His research has also been featured on television and radio broadcasts including NPR's Marketplace, the Today Show, and other national news outlets.
Thesis title: Epidemiologic characterization of human polyomaviruses in adults from the United States, and their relation to cutaneous squamous cell carcinomaWorking with Dr. Margaret R. Karagas, I investigate the seroepidemiology of human polyomaviruses, and their relation to skin cancer, in a large population-based case-control study. I hope to extend my research into the New Hampshire Birth Cohort, where I'd like to explore the association between infant health and measures of polyomavirus immunity. Having been given the opportunity to address novel hypotheses at the level acceptable for peer-reviewed publications, develop collaborations with other labs worldwide, and attend multiple conferences yearly with additional support from graduate school travel awards, I have greatly enjoyed my time with my research group.
Thesis title: Characterization of cancer risk and response to immunotherapy through pathway-based genomic analysesI am now doing clinical rotations in the final 2 years of the MD/PhD program following graduate study in QBS. I look forward to using my training in cancer genomics and big data as a physician-scientist who tailors precision therapy in one of the oncology specialties: medical oncology, surgical oncology, or radiation oncology. Current rotations will help guide that decision.
- **Qian DC**, Busam JA, Xiao X, Eeles RA, Schumacher FR, Phelan CM, O'Mara TA, Amos CI (2016) "seXY: A tool for sex inference from genotype arrays". Bioinformatics [accepted]
- **Qian DC**, Xiao X, Byun J, Suriawinata AA, Her SC, Amos CI, Barth RJ Jr (2016) "PI3K/Akt/mTOR signaling and plasma membrane proteins are implicated in responsiveness to adjuvant dendritic cell vaccination for metastatic colorectal cancer". Clin Cancer Res [epub ahead of print]
- **Qian DC** , Han Y, Byun J, Shin HR, Hung RJ, McLaughlin JR, Landi MT, Seminara D, Amos CI (2016) "A novel pathway-based approach improves lung cancer risk prediction using germline genetic variations". Cancer Epidemiol Biomarkers Prev 25, 12081215.
- Halloran JW, Zhu D,**Qian DC**, Byun J, Gorlova OY, Amos CI, Gorlov IP (2015) "Prediction of the gene expression in normal lung tissue by the gene expression in blood". BMC Med Genomics 8, 77:1‒6
- Qian DC, Byun J, Han Y, Greene CS, Field JK, Hung RJ, Brhane Y, McLaughlin JR, Fehringer G, Landi MT, Rosenberger A, Bickeböller H, Malhotra J, Risch A, Heinrich J, Hunter DJ, Henderson BE, Haiman CA, Schumacher FR, Eeles RA, Easton DF, Seminara D, Amos CI (2015) "Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions". Hum Mol Genet 24, 7406‒7420.
- Cordell HJ, Han Y, Mells GF, Li Y, Hirschfield GM, Greene CS, Xie G, Juran BD, Zhu D, Qian DC, Floyd JA, Morley KI, Prati D, Lleo A, Cusi D; Canadian-US PBC Consortium; Italian PBC Genetics Study Group; UK-PBC Consortium, Gershwin ME, Anderson CA, et al. (2015) "International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways". Nat Commun 6, 8019:1‒11.
- Onyango EO, Kelly AR, Qian DC, Gribble GW (2015) "Novel Synthesis of 1-bromo-8-methylnaphthalene and 1-bromo-5-methylnaphthalene". J Org Chem 80, 5970‒5972.
QBS Mentor: Scott Williams, PhD
I chose the QBS program because I was intrigued by the multidisciplinary aspect of the research. This gave me the ability to apply my knowledge of mathematics in a practical setting. I am working on applying network theory to novel genetic associations. I like working with Scott Williams because he encourages me to think independently, yet offers my guidance when I need it. I have come a long way in understanding since I joined his lab.