Redox Chemistry and Conformational Dynamics

Our group examines structural changes during folding and function of signaling proteins, with a particular emphasis on heme proteins and their redox-linked transformations. We employ a wide range of experimental approaches including development and synthesis of new protein dynamics probes, mutational analysis in vitro and in vivo, and time-resolved optical spectroscopy.

People News

New Group Members

Posted on December 17, 2013

Dr. Benjamin Levin (a recent BU graduate) has been working in our lab since September. Two new graduate students Dong Woo Shin (B. S. from Caltech) and Andrey Maskaev (M. S. from UM Duluth) joined the group. Welcome!

New Group Members

Posted on December 1, 2012

Dr. Xiaolei Chen from HKUST joined the lab. We welcome Soyeun Yang, our newest WISP intern.

Undergraduate Research Featured on Dartmouth Now

Posted on July 5, 2012

The Pletneva lab was recently featured in an article and a video about the strong commitment to undergraduate research at Dartmouth College in Dartmouth Now. Read more...

ICPP 7 Presentation

Posted on July 3, 2012

Kate described our research of cytochrome c conformational dynamics at the latest conference in Jeju, Korea.

Jason Toffey '12 Wins Chandler T. White 1916 Research Prize in Chemistry

Posted on June 6, 2012

Jason Toffey was awarded the Chandler T. White prize "... in recognition of outstanding performance in an independent research project." for his study of the kinetics of iso-1-cytochrome c.

Researchers Present at ACS National Meeting

Posted on March 28, 2012

Yuning Hong, Thomas Freeman, Jie Gu, Erik Snider, and AJ Vincelli all presented posters on their research projects. Kate also gave a talk on the work conducted on heme proteins in the lab.

Local Outreach and Relay for Life

Posted on May 18, 2011

The group presented our science stories at the Lebanon Middle School Science Cafe and participated in the walk and run to raise money for American Cancer Society this May.

NSF Honorable Mention

Posted on April 5, 2011

AJ has been awarded an Honorable Mention from the NSF Graduate Research Fellowship Program.

NSF CAREER Award

Posted on August 20, 2010

Kate has been awarded a 2010 NSF CAREER Award. This grant will fund our studies of "switchable" proteins. Read more...