Figure 1. In order to quantify the degree of vascularization in tumors that is related to angiogenesis, it is possible to label the endothelial cells in frozen sections with monoclonal antibody against CD31, and then count the microvessels to calculate the microvessel density.
Figure 2. We can also use confocal laser scanning fluorescence microscopy of ex vivo psoriatic skin to image the distribution of protoporphyrin IX after the skin has been incubated with 5-ALA.