CURRICULUM VITAE

PERSONAL DETAILS

Name:

OLEG Y. GRINBERG

Date of Birth:

September 16, 1944, Gaisin, Ukraine

Marital Status:

Married, two sons

Citizenship:

United States of America

Work Address:

HB 7785, 704 Vail
Dartmouth Medical School
Hanover, NH 03755-3863

Work Phone:

(603) 650-1806

Work Fax:

(603) 650-1717

e-mail:

olg@grinberg.net

Home Address:

20 Wolf Rd. Unit D69
Lebanon, NH, 03766

Home Phone:

(603) 448-0308

 

EDUCATION:
  • B.Sci., Physics, Physical Technical Institute, Moscow, Russia, 1965.
  • M.Sci., Molecular and Chemical Physics, Physical Technical Institute, Moscow, Russia, 1968.
  • Gradient student, Physical Technical Institute & Institute of Chemical Physics, Russian Academy of Science, 1968-1972
  • Ph.D., Chemical Physics, Academy of Science and Physical Technical Institute, Moscow, Russia, 1972.

 

EMPLOYMENT:
  • Research Associate Professor in the Department of Radiology, Dartmouth College, 1997-present; Visiting Scientist, Dartmouth College, 1992-1997, USA.
  • Chief of section (group of the labs), Leading Researcher at the Institute of Chemical Physics Russian Academy of Science (RAS), Moscow, 1989 -present; Chief of the group, Leading Researcher, 1988; Chief of the group, Senior Staff Scientist, 1980; Research Scientist, 1972, Research Assistant 1970; Engineer 1968, Institute of Chemical Physics Russian Academy of Science, Moscow, Russia.

 

CURRENT RESEARCH INTERESTS:
  • EPR spectroscopy: development High field EPR (2mm band) and Pulse EPR;
  • Chemical physics: photo chemistry, molecular motions and kinetic of the chemical reactions in liquids and polymers;
  • Biophysics: EPR oximetry, cell physiology and cardiovascular research.

 

PROFESSIONAL ACTIVITIES/HONORS:
  • Institute of Chemical Physics Annual Award in Chemical Physics 1973, 1986.
  • State prize winner of the USSR, "The development high resolution EPR methods",
    Diploma #20404, Moscow, 1988
  • Title Doctor of Science in Chemistry, Government Committee USSR,
    Diploma XM#001910, Moscow, 1989
  • Visiting Scientist, National Biomedical ESR Center, Medical College of Wisconsin, Milwaukee, USA, 1990.
  • Visiting Scientist, Dartmouth Medical School, Radiology Dep. Hanover NH, USA, 1992-present
  • Membership in International EPR Society

 

PUBLICATIONS AND PATENTS:
  • The full list consists more then 125 items.
  • 6 patents (in Russia).

 

EARLY SELECTED PUBLICATIONS (in English)
  1. O.Y.Grinberg, Y.S.Lebedev, A.A.Dubinsky, The Differential saturation of the EPR signals, Proceeding of the XVIth congress AMPERE Bucharest, 1971, p.293.
  2. O.Y.Grinberg, Y.S.Lebedev, A.A.Dubinsky, B.V.Ozherelyev, A.A.Chistota, The spatial distribution of Magnetic centers in solids as studied by "Forbidden" transitions. Mag. Res and Related Phenomena, Proc. of the XVIIth congress AMPERE, Turku (Finland), 1973, p.540.
  3. V.I.Barchuk, A.A.Dubinsky, O.Y.Grinberg, Y.S.Lebedev, Selective generation of radical pairs in benzoyl peroxide single crystals, irradiated by polarized U.V. light., Chem.Phys.Letters, 1975, 34(3), p.476.
  4. O.Y.Grinberg, A.A.Dubinsky, Y.S.Lebedev, Primary processes by radiolysis of solid paraffins: formation of radical pairs and isolated radicals, Fourth International Symposium on Radiations Chemistry, Hungary, Budapest, Abstracts, 1976, p.325.
  5. A.A.Dubinsky, A.P.Moravsky, V.F.Shuvalov, O.Y.Grinberg, Y.S.Lebedev, 2-mm band EPR of HO2 Radicals, XXth Congress AMPERE, Tallinn, 1978, Abstracts, D4305, p.571.
  6. O.Y.Grinberg, A.A.Dubinsky, Y.S.Lebedev, O.G.Poluektov, Molecular mobility as studied by EPR, Europhysics conference of macromolecular, Physics, Molecular Mobility in Polymer Systems, Leipzig DDR, 1981, Abstracts, 51, p.120-128.
  7. O.Y.Grinberg, Y.S.Lebedev, A.A.Dubinsky, O.G.Poluektov, M.A.Ondar, Free Radical Dynamics as studied by 2-mm ESR, Proc. of XXII congress AMPERE on Magnetic Resonance and Related Phenomena, Zurich, 1984, p.627-628.
  8. O.Y.Grinberg, Ya.S.Lebedev, A.A.Dubinsky, Yu.F.Panferov, Pulse Fourier Transform ESR spectroscopy, Proc. of XXII congress AMPERE on Magnetic Resonance and Related Phenomena, Zurich, 1984, p.617.
  9. O.G.Poluektov, A.A.Dubinsky, O.Ya.Grinberg, Ya.S.Lebedev, The use of 2-mm range Electron Spin Resonance Spectroscopy for Investigating Rotational Motions by Spin Probe Technique, Sov. Journ. of Chem. Phys., 1984, 1(11), p.2500-2516.
  10. O.Y.Grinberg, Y.S.Lebedev, L.I.Antsiferova, A.A.Dubinsky, V.I.Krynichny, E.V.Lubashevskaya, O.G.Poluektov, High Field ESR in studies of molecular Dynamics, 2nd conference of Modern Methods of Radiofrequency spectroscopy, Friedrichroda, DDR, 1985, p.48-57.
  11. O.G.Poluektov, A.A.Dubinsky, O.Ya.Grinberg, Ya.S.Lebedev, A Study of the Dynamics of Spin-labeled Macromolecules by Electron Spin Resonance in the 2-mm Band, Sov. Jour. of Chem. Phys., 1985, 2(2), p.30.
  12. O.G.Poluektov, A.A.Dubinsky, O.Y.Grinberg, Y.S.Lebedev, Model of Molecular Motion of Spin-Labeled Polymer as Studied by EPR in 3-cm and 2-mm Bands, Proceedings of VIII European Symposium on Polymer Spectroscopy, Budapest, Hungary, 1988, p.92.

 

PUBLICATIONS FOR THE LAST FEW YEARS:
  1. O.G.Poluektov, E.V.Lubashevskaya, A.A.Dubinsky, O.Y.Grinberg, L.I.Antsiferova, Y.S.Lebedev, Determination of the Model of Isotropic Rotational Motion from 2mm Band ESR Spectra, Sov. Jour. of Chem. Phys., 1989, 4(12), p.2683.
  2. A.I.Smirnov, O.G.Poluektov, O.Y.Grinberg, A.A.Dubinsky, V.N.Krimov, A.R.Kaul, I.E.Graboi and Y.S.Lebedev, Absorption of Magnetic and Electric Components of Microwave Field in High Temperature Superconductors, Chim. Phys. (russ), 1989, 8(2), p.221-224.
  3. O.G.Poluektov, O.Y.Grinberg, A.A.Dubinsky, O.Y.Sidorov and Y.S.Lebedev, Study of Dynamics of Spin Labeled Polymers by 3cm and 2mm Band EPR, Teor. i Exper. Chim. (russ), 1989, 26(4), p.459-466.
  4. E.V.Gal'tseva, O.Y.Grinberg, A.A.Dubinsky, G.G.Lazarev, Y.S.Lebedev, O.G.Poluektov, A.I.Smirnov and O.E.Yakimchenko, Magnetic Radio Spectroscopy and Inverse Tomography of High Temperature Superconductors, Proceedings of XXIV AMPERE Congress on Magnetic Resonance and Related Phenomena, Poznan, 1989, p.461- 477.
  5. G.I.Todorov, O.G.Poluektov, A.N.Petrov, O.Y.Grinberg and Y.S.Lebedev, Molecular Mobility and Kinetics of Oxidation of Nitroxide Radicals in Micellar Systems, Proceedings of VII Conference on Magnetic Resonance in Biology and Medicine (russ), Zvenigorod, 1989, p.276-277.
  6. V.I.Krinichni, O.Y.Grinberg, G.I.Kozub and Y.S.Lebedev, Study of High Temperature Superconductors by Macro Spin Probe, Chim. Phys. (russ), 1989, 8(3), p.423-424.
  7. O.G.Poluectov, O.Y.Grinberg, A.A.Dubinsky, O.Y.Sidorov and Y.S.Lebedev, Dynamic Characteristics and Intermolecular Interactions of Nitroxyl Radicals in Polar Solvents, Sov. Jour. of Chem. Phys., (russ), 1990, 5(6), p.1375.
  8. O.Y.Grinberg, A.A.Dubinsky, O.G.Poluektov and Y.S.Lebedev, Perchloride-3-phenylmethyl Radical as a New Spin Probe without SHI Structure, Jour. Physich. Chim. (russ), 1990, 64(6), p.1586-1591.
  9. E.V.Lubashevskaya, O.G.Poluektov, A.A.Dubinsky, O.Y.Grinberg, L.I.Antsiferova and Y.S.Lebedev, Investigation of Models for Anisotropic Molecular Motion in Vitrified Matrices Using ESR in the Two-millimeter Range, Sov. Jour. of Chem. Phys. (russ), 1990, 5(8), p.1857-1867.
  10. O.Y.Grinberg, A.A.Dubinskii, O.G.Poluektov and Y.S.Lebedev, Study of Orientational Order in Liquid Crystals by the Spin Label Technique in the 2mm EPR Range, Sov. Jour. of Chem. Phys. (russ), 1990, 6(10), p.2685-2704.
  11. E.V.Lubashevskaya, L.I.Antsiferova, O.G.Poluektov, O.Y.Grinberg, A.A.Dubinskii and Y.S.Lebedev, Motion Model for an Analysis of Molecular Mobility of Spin Probes, Sov. Jour. of Chem. Phys. (russ), 1990, 7(4), p.940-945.
  12. E.V.Lunina, A.D.Litvina, A.E.Rasumaeva, L.I.Antsiferova, Y.S.Lebedev, O.Y.Grinberg and O.G.Poluektov, Complexes of Nitroxide Radicals with Acids, Proceedings of V Conference on Modern Methods of EPR and NMR Spectroscopy in Solid State Chemistry (russ), Chernogolovka, 1990, p.139-141.
  13. Y.S.Lebedev, O.Y.Grinberg, A.A.Dubinsky and O.G.Poluektov, Investigation of Spin Labels and Probes by Millimeter Band EPR in BIOACTIVE SPIN LABELS, Renat I.Zhdanov (Ed), Springer-Verlag, 1992, p.227.
  14. D.H.Powell, E.Brucher, G.Gonzales, O.Y.Grinberg, K.Kohler, Y.S.Lebedev, A.E.Merbach, K.Micskei, F.Ottaviani and A.von Zelewsky, Magnetic Field Dependent Electronic Relaxation of Gd3+ in Aqueous Solutions of the Complexes [Gd(H2O)8]3+, [Gd(PDTA)(H2O)2]- and [Gd(DTPA-BMA)(H2O)] of Interest in Magnetic Resonance Imaging, Helv. Chim. Acta, 1993, 76(5), 2129-2146.
  15. S.D.Chemerisov, D.S.Tipikin, O.Y.Grinberg and Y.S.Lebedev, Thermal polarization of spins and sings of spin-spin coupling constants in radical pairs, Chim. Phys. (russ), 1993, 67(11), p.1999.
  16. V.E.Galtsev, O.Y.Grinberg, Y.S.Lebedev and E.V.Galtseva, EPR Dosimetry Sensitivity Enhancement by Detection of Rapid Passage Signal of the Tooth Enamel at Low Temperature, Appl. Magn. Reson., 4, 1993 pp.331-333.
  17. V.E.Galtsev, E.V.Galtseva O.Y.Grinberg, Y.S.Lebedev, Human Tooth EPR Dosimetry Enhancement Sensitivity, J. Radioanal. Nucl. Chem., Letters 186(1) 1994, pp.35-45.
  18. V.E.Gal'tsev, E.V.Gal'tseva, O.Y.Grinberg and Y.S.Lebedev, Improvement of Sensitivity of ESR Dosimetry of Tooth Enamel, Doklady Biophysics, Vol.334-336, 1994, pp.9-12,
  19. V.E.Galtsev, E.V.Galtseva, O.Y.Grinberg, Y.S.Lebedev, Human EPR Dosimetry with Enhanced Sensitivity, Magnetic Resonance and Related Phenomena, XXVIIth Congress AMPERE (absracts Vol.1), Kazan, 1994, pp.434-435.
  20. V.E.Gal'tsev, O.Y.Grinberg and B.V.Novozilov, Determination the Diffusion Coefficient and Reaction Rate Constant of Oxygen Dissolution in Oil by EPR, Sov.J.Chem.Phys. Vol.12(4) 1994, pp.788- 797.
  21. V.E.Gal'tsev, O.Y.Grinberg, A.N.Ratov, G.B.Nemirovskaya and A.S.Emel'yanova, Localization of Vanadil Complexes in Poliaromatic Structures of Oil, Doklady Chemistry, Vol.334(1-3), 1994 pp.19-21.
  22. V.E.Galtsev, I.M.Ametov, O.Y.Grinberg, ENDOR Study of Asphaltene Association in Oil, Magnetic Resonance and Related Phenomena, XXVIIth Congress AMPERE (absracts Vol.1), Kazan, 1994, pp.432-433.
  23. P.E.James, F.Goda, O.Y.Grinberg, K.J.Liu, S.K.Jackson and H.M.Swartz, Intra-renal Oxygenation During Experimental Endotoxemia: An EPR Oximetry Study. 36th Conference on Analytical Chemistry, Denver, Colorado, USA, 1994.
  24. H.M.Swartz, G.Bacic, B.J.Friedman, F.Goda, O.Y.Grinberg, P.J. Hoopes, J.J.Jiang, K.J.Liu, T.Nakashima, J.O'Hara, T.Walczak, Measurement of pO2 in Vivo, Including Human Subjects by Electron Paramagnetic Resonance" in Oxygen Transport in Tissue XVI, M.C.Hogan et al., (Ed), Plenum Press, New York, pp 119-128, 1995.
  25. S.D.Chemerisov, O.Y.Grinberg, D.S.Tipikin, Y.S.Lebedev, H.Kurreck and K.Mobius, Mechanically Induced Radical Pair Formation in Porphyrin-Quinone and Related Donor-Acceptor Mixtures: Unusual Stability and Zero-Field Splitings, Chem.Phys. Letters, 219:353-361,1994.
  26. P.E.James, S.K.Jackson, O.Y.Grinberg and H.M.Swartz, The Effects of Endotoxin on Oxygen Consumption of Various Cell Types in vitro: An EPR Oximetry Study. Free Radical Biology and Medicine, 18:641-647,1995.
  27. P.E.James, G.Bacic, O.Y.Grinberg, F.Goda, J.Dunn, S.K.Jackson and H.M.Swartz, Endotoxin Induced Changes in Intrarenal pO2 Measured by In Vivo Electron Paramagnetic Resonance Oximetry and Magnetic Resonance Imaging, Free Rad. Biol. Med., In Press,1995.
  28. B.J.Friedman, O.Y.Grinberg and H.M.Swartz, Measurement of myocardial oxygen tension and capillary density in the isolated perfused heart. Circ 92, Supp I - 445, 1995.
  29. B. J. Friedman, O. Y. Grinberg, K. Isaacs, T. M. Walczak, and H. M. Swartz, Myocardial Oxygen Tension and Relative Capillary Density in Isolated Perfused Rat Hearts, J. Mol. Cell. Cardiol., 27,1995.
  30. P.E.James, O.Y.Grinberg, G.Michaels and H.M.Swartz, Intraphagosomal Oxygen in Stimulated Macrophages, J. of Cellular Physiology, 163:241-247, 1995.
  31. S.D.Chemerisov, A.I.Kokorin, O.Ya.Grinberg Ya.S.Lebedev, The study of the Electron Spin Exchange Efficiency in Liquid Solutions of Radicals at Various EPR Frequencies, Appl. Magn. Reson. 9:37-43,1995.
  32. B.J.Friedman, O.Y.Grinberg, K.A.Isaacs, E.K.Ruuge and H.M.Swartz Effect of Repetitive Ischemia on Local Myocardial Oxygen Tension in Isolated Perfused and Hypoperfused Rat Hearts, Magn. Reson. Med., 35, 1996.
  33. O.Y.Grinberg, S.A.Grinberg, B.J.Friedman and H.M.Swartz, Myocardial Oxygen Tension and Capillary Density In Isolated Perfused Rat Hearts During Pharmacological Intervention. Oxygen Transport to Tissue XVIII, 171-181, Plenum Press, NY, 1997.
  34. O.Y. Grinberg, B.J. Friedman, and H.M. Swartz, "Intramyocardial pO2 Measured by EPR," Oxygen Transport to Tissue XIX, In Press (1997).
  35. J.A. O’Hara, P.E. James, T. Panz, O. Grinberg, N. Jain, J. Dunn, and H.M. Swartz, "Determining the Position and Effects in Tumors of Gloxy, an Oxygen Sensitive Paramagnetic Material," Oxygen Transport to Tissue XIX, In Press (1997).
  36. P.E. James, J. A. O’Hara, O.Y. Grinberg, T. Panz and H.M.Swartz, "Intratumoral pO2 Measured Using a New Oxygen Sensitive Paramagnetic Material, Gloxy," Oxygen Transport to Tissue XIX, In Press (1997).
  37. H.M. Swartz, J. Dunn, O. Grinberg, J. O’Hara, T. Walczak, "What Does EPR Oximetry with Solid Particles Measure--And How Does This Relate to Other Measures of pO2?", Oxygen Transport to Tissue XIX, In Press (1997).
  38. P. James, O. Grinberg, F. Goda, T. Panz, J. O’Hara, and H. M. Swartz, "Gloxy: An Oxygen-Sensitive Coal for Accurate Measurement of Low Oxygen Tensions in Biological Systems," Magn. Reson. Med., 38:48-58 (1997).
  39. P.E. James, O.Y. Grinberg, and H.M. Swartz, "Superoxide Production by Phagocytosing Macrophages in Relation to the Intracellular Distribution of Oxygen," Submitted.
  40. P.E. James, F. Goda, O.Y. Grinberg, K.G. Szybinski and H.M. Swartz, "Intrarenal pO2 Measured by EPR Oximetry and the Effects of Bacterial Endotoxin," Oxygen Transport to Tissue XVIII, 557-569 (1997).