Pathology of Lymph Nodes Self Assessment


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  1. B lymphocytes home to which region of the lymph node? More information

    Cortex

    Interfollicular region

    Subcortical sinus

    Medullary sinus

    All of the above


  2. Indolent lymphomas More information

    Have a long median survival

    Usually have a high mitotic rate

    Display prominent nucleoli

    Are usually curable

    Are arrested at a precursor stage of development


  3. Aggressive lymphomas: More information

    Are arrested at differentiation phases normally associated with low proliferation

    Rarely display nucleoli

    Do not respond to chemotherapy

    Are potentially curable

    Are rarely seen in children


  4. All of the following are true about follicular lymphomas except More information

    Mimic differentiated cell types

    FL are often disseminated at diagnosis

    Are curable 40% of the time

    Initially respond to most chemotherapy

    Are rare in childhood


  5. . More information

    Which choice best describes this image?

    Indolent lymphoma

    Low mitotic rate

    Condensed chromatin

    Small cleaved lymphoma

    Diffuse large cell lymphoma


  6. . More information

    Which choice best describes this image?

    Large cell lymphoma

    Small cleaved lymphoma

    Burkitt lymphoma

    Small lymphocytic lymphoma

    Lymphoblastic lymphoma


  7. The Reed Sternberg cell is associated with which disease More information

    Burkitt's lymphoma

    Follicular lymphoma

    Mantle cell lymphoma

    Large B cell lymphoma

    Hodgkin's lymphoma


  8. A lymphoma is analyzed by flow cytometry, and the following results are obtained: More information

    CD10 positive
    CD3 (T cell) negative
    CD5 (T cell) negative
    Kappa light chain 90%
    Lambda light chain 3%

    What answer best describes these findings

    Monoclonal lambda B cell lymphoma

    Monoclonal kappa B cell lymphoma

    Hodgkin's lymphoma

    B lymphoblastic lymphoma

    Reactive lymph node


  9. All of the following are true about Flow cytometry except More information

    FC can detect a clonal B cell population

    FC eliminates the need for microscopy

    FC is computer assisted fluorescent microscopy

    FC can distinguish a B from T lineage lymphoma

    FC can distinguish subtypes of T and B cell lymhoma


  10. Prognosis in lymphoma is based on all of the following except More information

    Race

    Stage of disease

    Age

    Histologic type

    International prognostic index


  11. . More information

    What are these things?

    Burkitt cells

    Hairy cells

    Reed-Sternberg cells

    Small cleaved cells

    Mantle cells


  12. Of all the following, which is the most curable More information

    Hodgkin's lymphoma

    Follicular lymphoma

    Small lymphocytic lymphoma

    Peripheral T cell lymphoma

    Mantle cell lymphoma


  13. Which of the following is true about Peripheral T cell lymphomas More information

    They are diseases of childhood

    They tend to involve extranodal sites, with characteristic clinical syndromes

    Clonality is easily detected by flow cytometry

    They are usually curable

    Most are indolent lymphomas


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