Mission Statement

The mission of the Dartmouth College Molecular Biology and Proteomics Core Facility is to provide products, services and support to help investigators solve basic and clinical research problems related to macromolecules (DNA, RNA, proteins) of biomedical interest. It is our goal to offer the highest quality products and services possible at reasonable prices. The charges to investigators can never be more than the cost of time and materials. In some instances we will not always be able to directly compete with outside providers based on price alone. However, we offer some services which are not generally commercially available or the commercial service is not cost-effective for the researcher to use. In addition to competitive pricing, what the MB&P core can offer that commercial services cannot is a higher quality product or service, rapid access and turn-around time, a "money-back" guarantee, and detailed and expert advice and support to the research community. The overall goal of the facility is to become a valuable and responsive in-house resource for helping investigators obtain their research objectives involving macromolecular sequencing and synthesis.

The current services we offer are DNA sequencing, protein identification, and DNA synthesis. In addition, the Core is responsible for the care and upkeep of twelve instruments available for use by individuals on a walk-up basis. The current equipment list is posted under General Information. All services are performed on a first-come-first-served basis unless otherwise noted in the individual service protocols. Charges for services will be made directly to investigator accounts.

The MB Core currently has four full-time staff members. The Core facility itself is open 7:30am to 5pm Monday through Friday and is also available by email and FAX. The Core is fiscally managed by the Norris Cotton Cancer Center (NCCC) as a shared resource. The director of this resource oversees the operation of the Core. The director also serves as chair for a faculty MB&P Core Advisory Committee which meets quarterly and reports to the NCCC Executive Committee. In addition to the charge-back system for services, the budget for the MB&P Core is currently underwritten by funds from the NCCC Core Grant, the Dartmouth Toxic Metals Research Program, and the Cellular and Molecular Mechanisms of Lung Disease COBRE Program.



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