A.Gill, A. Birdsey-Benson, B.L. Jones, L.P. Henderson, D.R. Madden (2008) Correlating AMPA receptor activation and cleft closure across subunits: crystal structures of the GluR4 ligand-binding domain in complex with full and partial agonists. Biochemistry, 47, 13831-13841.

P.R. Cushing, A. Fellows, D. Villone, P. Boisguérin, D.R. Madden (2008) The relative binding affinities of PDZ partners for CFTR: a biochemical basis for efficient endocytic recycling. Biochemistry 47, 10084-10098.

C.R. Midgett, D.R. Madden (2007) Breaking the bottleneck: eukaryotic membrane protein expression for high-resolution structural studies. J Struct. Biol., 160, 265-274.

D.R. Madden, M. Safferling (2007) Baculoviral expression of an integral membrane protein for structural studies. Methods Mol Biol. 363, 39-57.

M. Wolde, A. Fellows, J. Cheng, A. Kivenson, B. Coutermarsh, L. Talebian, K. Karlson, A. Piserchio, D.F. Mierke, B.A. Stanton, W.B. Guggino, D.R. Madden (2007) Targeting CAL as a negative regulator of DeltaF508-CFTR cell-surface expression: an RNA interference and structure-based mutagenetic approach. J Biol Chem. 282, 8099-8109

Madden, DR. (2005) New light on an open-and-shut case. Nature Chem. Biol. 1, 317-319.

A. Piserchio, A. Fellows, D.R. Madden, and D.F. Mierke (2005) Association of the cystic fibrosis transmembrane conductance regulator with CAL: structural features and molecular dynamics. Biochemistry 44, 16158-16166.

J. Féthière, D. Venzke, D.R. Madden, and B. Böttcher (2005) Peripheral stator of the yeast V-ATPase: stoichiometry and specificity of interaction between the EG-complex and subunits C and H. Biochemistry 44, 15906-15914.

D.R. Madden, N. Armstrong, D. Svergun, J. Pérez and P. Vachette (2005) Solution X-ray scattering evidence for agonist- and antagonist-induced modulation of cleft closure in a glutamate receptor ligand-binding domain. J Biol Chem. 280, 23637-23642.

A. Gill and D.R. Madden (2005). Glutamate receptor ion channels: structural insights into molecular mechanisms. In The Structural Biology of Membrane Proteins (Buchanan, S, and Grisshammer, R, eds.), Cambridge, UK: Royal Society of Chemistry.

D.R. Madden, Q. Cheng, S. Thiran, S. Rajan, F. Rigo, K. Keinänen, S. Reinelt, H. Zimmermann and V. Jayaraman (2004) Stereochemistry of glutamate receptor agonist efficacy: engineering a dual-specificity AMPA/kainate receptor. Biochemistry 43, 15838-15844.

W. Tichelaar, M. Safferling, K. Keinänen, H. Stark and D.R. Madden (2004) The three-dimensional structure of an ionotropic glutamate receptor reveals a dimer-of-dimers assembly. J Mol Biol. 344, 435-442.

S. Reinelt, E. Hofmann, T. Gerharz, M. Bott and D.R. Madden (2003) The structure of the periplasmic ligand-binding domain of the sensor kinase CitA reveals the first extracellular PAS domain. J Biol Chem. 278, 39189-39196.

A. Pasternack, S.K. Coleman, J. Féthière, D.R. Madden, J.P. LeCaer, J. Rossier, M. Pasternack, K. Keinänen K. (2003) Characterization of the functional role of the N-glycans in the AMPA receptor ligand-binding domain. J Neurochem. 85, 1184-1192

D.R. Madden (2002) The inner workings of the AMPA receptors. Curr Opin Drug Discov Devel. 5, 741-748

D.R. Madden (2002) The structure and function of glutamate receptor ion channels. Nature Rev. Neurosci. 3, 91-101.

B. Klockow, W. Tichelaar, D.R. Madden, H.H. Niemann, T. Akiba, K. Hirose, D.J. Manstein (2002) The dynamin A ring complex: molecular organization and nucleotide-dependent conformational changes. EMBO J. 21, 240-250

M. Safferling, W. Tichelaar, G Kümmerle, A. Jouppila, A. Kuusinen, K. Keinänen and D.R. Madden (2001) First images of a glutamate receptor ion channel: oligomeric state and molecular dimensions of GluRB homomers. Biochemistry, 40, 13948-13953.

D.R. Madden, S. Thiran, H. Zimmermann, J. Romm and V. Jayaraman (2001) Stereochemistry of quinoxaline antagonist binding to a glutamate receptor investigated by Fourier transform infrared spectroscopy. J Biol Chem., 276, 37821-37826.

J. Féthière, A. Andersson, K. Keinänen and D.R. Madden (2000) Crystallization of an AMPA receptor binding domain without agonist: importance of carbohydrate content and crystal freezing conditions. Acta Cryst., D56, 1625-1629.

V. Jayaraman, R. Keesey, D.R. Madden. (2000) Ligand--protein interactions in the glutamate receptor. Biochemistry, 39, 8693-8697

V. Jayaraman, S. Thiran, D.R. Madden (2000) Fourier transform infrared spectroscopic characterization of a photolabile precursor of glutamate. FEBS Lett., 475, 278-282

D.R. Madden, R. Abele, A. Andersson, K. Keinänen (2000) Large-scale expression and thermodynamic characterization of a glutamate receptor agonist-binding domain. Eur J Biochem., 267, 4281-4289

R. Abele, K. Keinänen and D.R. Madden (2000) Agonist-induced isomerization in a glutamate receptor ligand-binding domain: a kinetic and mutagenetic analysis. J Biol Chem. 275, 21355-21363.

A. Kuusinen, R. Abele, D.R. Madden, K. Keinänen (1999) Oligomerization and ligand-binding properties of the ectodomain of the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunit GluRD. J Biol Chem. 274, 28937-28943

R. Abele, D. Svergun, K. Keinänen, M.H. Koch, D.R. Madden (1999) A molecular envelope of the ligand-binding domain of a glutamate receptor in the presence and absence of agonist. Biochemistry, 38, 10949-10957

R. Abele, M. Lampinen, K. Keinänen, D.R. Madden, (1998) Disulfide bonding and cysteine accessibility in the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor subunit GluRD. Implications for redox modulation of glutamate receptors. J Biol Chem. 273, 25132-25138