Lung Biology Center Pilot Projects

Funded by an NIH IDeA Program COBRE, a Cystic Fibrosis Foundation Research Development Program, and the Geisel School of Medicine

Systems-Level Analysis of P. aeruginosa Response to Antibiotics with ADAGE

Project Leader: Deborah A. Hogan, Ph.D.

Respiratory Virus Infection and Pseudomonas Virulence in Cystic Fibrosis

Project Leader: Richard I. Enelow, M.D.
Co-Investigator: Peter Wright, M.D.

Mechanisms of Regional Heterogeneity of Lung Macrophage Inflammation

Project Leader: Alix Ashare, M.D., Ph.D.

Development of cFLIP-Calmodulin Interaction Inhibitors for Lung Cancer Therapy

Project Leader: Maria Pellegrini, Ph.D.
Co-Investigator: Dale F. Mierke, Ph.D.

Microbial Activity as a Determinant of Health Status in Cystic Fibrosis

Project Leader: Alex H. Gifford, M.D.

Promoting the Phagocytic Clearance of Non-Motile P. Aeruginosa

Project Leader: Brent L. Berwin, Ph.D.
Co-Investigator: Scott Gerber, Ph.D.

A Novel Murine Model of Allergic Bronchopulmonary Aspergillosis

Project Leader: Robert A. Cramer, Ph.D.
Co-Investigator: Joshua J. Obar, Ph.D.

Monitoring Efforts to Clear P. aeruginosa in Cystic Fibrosis Patients

Project Leader: Jane E. Hill, Ph.D.

Linking Disease Outcomes to the Gut Microbiota in Infants and Children with CF

Project Leader: Todd A. MacKenzie, Ph.D.
Co-Investigators: Juliette C. Madan, M.D., M.S.; George A. O'Toole, Ph.D.