COBRE Center for Lung Biology Research
Lung disease is the third most frequent cause of death in this country, claiming ~360,000 Americans annually. Tragically, an additional 25 million live with chronic lung diseases, including asthma, emphysema, cancer and cystic fibrosis. Unfortunately, the number of individuals with lung disease is increasing at an alarming rate, thus, a better understanding of the etiology of lung disease and new therapeutics to treat lung disease are required.
The goals of the Dartmouth Lung Biology Center, funded by a COBRE award by the NCRR and NIGMS since 2003 (P20-RR018787/GM103413 and P30-GM106394), are to enhance the research efforts of our faculty and students by:
Integration of the COBRE supported Cores (Host Pathogen Integration Core, Live Cell Imaging Core, and Translational Research Core) with shared services in the Geisel School of Medicine at Dartmouth, Dartmouth Hitchcock Medical Center(DHMC) and other IDeA supported Cores, including Bioinformatics and Biostatistics;
Fostering synergistic scientific collaboration through the COBRE Research Projects, associated Cores, and other basic and translational infrastructure and programs at the Geisel School of Medicine at Dartmouth/DHMC, including the Immunology COBRE, the Bioinformatics COBRE, the Center for Epidemiology COBRE, and the Dartmouth INBRE programs;
Mentoring and supporting the career development of all faculty in the program, and;
Providing administrative support.
Project Leader: Dean Madden, Ph.D.
Project Leader: Alix Ashare, M.D., Ph.D.
Co-Investigator: Deborah A. Hogan, Ph.D.
Project Leader: Mitsuo Matsuoka, MD, Ph.D.
Co-Investigator: Richard I. Enelow, M.D.
Project Leader: Ambrose Cheung, M.D.
Project Leader: Maria Pellegrini, Ph.D.
Co-Investigator: Dale F. Mierke, Ph.D.
Project Leader: Robert A Cramer, Ph.D.
Project Leader and Investigator: George A O'Toole, Ph.D.
Project Leader: Karl E. Griswold, Ph.D.
Co-Investigator: Brent Berwin, Ph.D.
Project Leader: Joseph Schwartzman, M.D.
Project Leader: Manuel Vilchez, M.D.
Co-Investigators: Richard Zuckerman, M.D., M.P.H., Harold Manning, M.D., George A O'Toole, Ph.D.