Dr. Tadashi Honda

Presentation List


1. Saponins from Terminalia arjuna. T. Honda, T. Murae, T. Tsuyuki, and T. Takahashi; Thirty-second Annual Meeting of the Chemical Society of Japan, (April, 1975),Tokyo, Japan.

2. Forced Wolff-Kishner Reduction of Olean-12-en-19-one Derivatives. T. Honda, T. Murae, T. Tsuyuki, and T. Takahashi; Thirty-sixth Annual Meeting of the Chemical Society of Japan, (April, 1977), Osaka, Japan.

3. Synthetic Studies of Quassinoids I. T. Honda, T. Murae, and T. Takahashi; Twenty-second Meeting on the Chemistry of Perfumes, Terpenoids, and Essential Oils, (October, 1978), Yokohama, Japan.

4. Synthetic Studies of Quassinoids II. T. Honda, T. Murae, H. Kawai, and T. Takahashi; Twenty-second Meeting on the Chemistry of Perfumes, Terpenoids, and Essential Oils, (October, 1978), Yokohama, Japan.

5. Synthesis of 14aH-Picrasane Derivatives. T. Honda, T. Murae, Y. Kurata, S. Ohta, H. Hirota, Y. Iitaka, A. Itai, and T. Takahashi; Forty-third Annual Meeting of the Chemical Society of Japan, (April, 1981), Tokyo, Japan.

6. Synthetic Studies of Quassinoids. T. Murae, T. Honda, S. Ohta, Y. Kurata, H. Matsuo, and T. Takahashi; Twenty-fourth Meeting on the Chemistry of Natural Products, (October, 1981), Osaka, Japan.

7. Studies on Antitumor Activity of Quassinoids I -Synthesis of Dehydroailanthinone and Novel Ailanthone Derivatives. T. Honda, K. Imao, M. Inoue, N. Nakatsuka, T. Tatsuoka, and T. Nakanishi; Hundred Third Annual Meeting of the Pharmaceutical Society of Japan, (April, 1983), Tokyo, Japan.

8. Studies on Antitumor Activity of Quassinoids II -Synthesis of Bruceantine, Bruceantinol, and Novel Bruceolide derivatives. T. Honda, K. Imao, M. Inoue, N. Nakatsuka, T. Tatsuoka, and T. Nakanishi; Hundred Third Annual Meeting of the Pharmaceutical Society of Japan, (April, 1983), Tokyo, Japan.

9. Studies on Antitumor Activity of Novel Ailanthone Derivatives. T. Honda, N. Nakatsuka, T. Tatsuoka, M. Matsui, T. Miura, Y. Fukuda, and T. Nakanishi; Forty-second Annual Meeting of the Japanese Cancer Association, (October, 1983), Nagoya, Japan.

10. Studies on Antitumor Activity of Quassinoids IV -Synthesis and Antitumor Activity of SUN2071 and Its Analogs. T. Honda, M. Inoue, K. Imao, N. Nakatsuka, T. Tatsuoka, T. Nakanishi, and T. Noguchi; Hundred Fourth Annual Meeting of the Pharmaceutical Society of Japan, (March, 1984), Sendai, Japan.

11. Studies on Antitumor Activity of Quassinoids V -Structure-Activity Relationships of Antitumor Quassinoids. T. Honda, M. Inoue, K. Imao, N. Nakatsuka, T. Tatsuoka, T. Nakanishi, and T. Noguchi; Hundred Fourth Annual Meeting of the Pharmaceutical Society of Japan, (March, 1984), Sendai, Japan.

12. Constituents of Seeds of Brucea javanica (Yadanzi) I -Structure of Yadanziolide A, B, and C. S. Yoshimura, T. Sakaki, M. Ishibashi, T. Tsuyuki, T. Takahashi, T. Honda, and T. Nakanishi; Twenty-eighth Meeting on the Chemistry of Perfumes, Terpenoids, and Essential Oils, (October, 1984), Kanazawa, Japan.

13. Constituents of Seeds of Brucea javanica (Yadanzi) II-Structure of Yadanzioside A-H. T. Sakaki, S. Yoshimura, M. Ishibashi, T. Tsuyuki, T. Takahashi, T. Honda, and T. Nakanishi; Twenty-eighth Meeting on the Chemistry of Perfumes, Terpenoids, and Essential Oils, (October, 1984), Kanazawa, Japan.

14. Constituents of Seeds of Brucea javanica (Yadanzi) III -Structure of Yadanziolide D. S. Yoshimura, T. Sakaki, M. Ishibashi, T. Tsuyuki, T. Takahashi, K. Matsushita, and T. Honda; Fiftieth Annual Meeting of the Chemical Society of Japan, (April, 1985), Tokyo, Japan.

15. Constituents of Seeds of Brucea javanica (Yadanzi) IV -Structure of Yadanzioside K and M. T. Sakaki, S. Yoshimura, M. Ishibashi, T. Tsuyuki, T. Takahashi, T. Honda, and T. Nakanishi; Fiftieth Annual Meeting of the Chemical Society of Japan, (April, 1985), Tokyo, Japan.

16. Constituents of Seeds of Brucea javanica (Yadanzi) V -Structure of Yadanzioside I, J, and L. S. Yoshimura, T. Sakaki, M. Ishibashi, T. Tsuyuki, T. Takahashi, T. Honda, and T. Nakanishi; Fiftieth Annual Meeting of the Chemical Society of Japan, (April, 1985), Tokyo, Japan.

17. Isolation and Structure of Antileukemic Bitter Principles from Ya-dan-zi (Brucea javanica (L.) Merr). S. Yoshimura, T. Sakaki, M. Ishibashi, T. Tsuyuki, T. Takahashi, T. Honda, T. Nakanishi, and K. Matsushita; Twenty-seventh Meeting on the Chemistry of Natural Products, (October, 1985), Hiroshima, Japan.

18. Studies on Antitumor Activity of Quassinoids - Synthesis and Antitumor Activity of Novel Ailanthone Analogs. T. Honda, K. Imao, M. Inoue-Shiraishi, N. Nakatsuka, T. Tatsuoka, T. Nakanishi, and T. Noguchi; Sixth Symposium on the Development and Application of Naturally Occurring Drug Materials, (July, 1986), Nagoya, Japan.

19. Synthesis and Antitumor Activity of Ellipticine Nucleoside Derivatives. T. Honda, M. Inoue, M. Kato, T. Nakanishi, and T. Noguchi; Forty-fifth Annual Meeting of the Japanese Cancer Association, (October, 1986), Sapporo, Japan.

20. Synthesis of Antitumor Ellipticine Glycosides II -Drug Design and Synthetic Studies. T. Honda, M. Inoue, M. Kato, and K. Shima; Hundred Seventh Annual Meeting of the Pharmaceutical Society of Japan, (April, 1987), Kyoto, Japan.

21. Synthesis of Antitumor Ellipticine Glycosides III -Synthesis and Antitumor Activity of Ellipticine Glycosides. T. Honda, M. Inoue, M. Kato, K. Shima, T. Nakanishi, and T. Noguchi; Hundred Seventh Annual Meeting of the Pharmaceutical Society of Japan, (April, 1987), Kyoto, Japan.

22. Synthesis of Antitumor Ellipticine Glycosides IV -Synthesis of SUN4599 (Elliprabin). T. Honda, M. Kato, T. Shimamoto, K. Shima, M. Inoue, T. Yoshida, T. Nakanishi, and T. Noguchi; Hundred Seventh Annual Meeting of the Pharmaceutical Society of Japan, (April, 1987), Kyoto, Japan.

23. Antitumor Effects of Ellipticine Glycosides, SUN4599 against Human Tumor Cells (CAM Method). J. Hashino, Y. Fukuda, T. Nakanishi, T. Honda, T. Sasaki, and T. Noguchi, Forty-sixth Annual Meeting of the Japanese Cancer Association, (September, 1987), Tokyo, Japan.

24. Antitumor Effects of Ellipticine Glycosides, SUN4599 against Human Tumor Cells (SRC Method). T. Yoshida, Y. Fukuda, K. Sugiyama, T. Nakanishi, T. Honda, M. Kato, and T. Noguchi; Forty-sixth Annual Meeting of the Japanese Cancer Association, (September, 1987), Tokyo, Japan.

25. Molecular Mechanics Aided Structure Determination, Yadanziolide D. S. Yoshimura, K. Ogawa, T. Tsuyuki, T. Takahashi, and T. Honda; Sixteenth International Symposium on the Chemistry of Natural Products (IUPAC), (May 29 - June 3, 1988), Kyoto, Japan.

26. Studies on Mechanism of Action of SUN4599. Y. Yoshimura, M. Matsui, T. Honda, T. Nakanishi, and T. Noguchi; Forty-seventh Annual Meeting of the Japanese Cancer Association, (September, 1988), Tokyo, Japan.

27. Inhibitory Effect of SUN4599 on Metastasis of Murine Tumor. Y. Fukuda, J. Hashino, T. Yoshida, T. Nakanishi, T. Honda, T. Tsuruo, and T. Noguchi; Forty-seventh Annual Meeting of the Japanese Cancer Association, (September, 1988), Tokyo, Japan.

28. Studies on SUN4599 (2-a-L-Arabinopyranosyl-9-hydroxyellipticinium Bromide), A Novel and Highly Active Antitumor Agent. T. Honda, M. Kato, T. Shimamoto, M. Inoue, K. Shima, T. Nakanishi, and T. Noguchi; Ninth Symposium on Medicinal Chemistry, (November, 1988), Tokyo, Japan.

29. Evaluation of Quassinoids for Amoebacidal Activity in Vitro and in Vivo. S. Kobayashi, T. Takeuchi, and T. Honda; Eighth International Congress of Protozoology, (1989), Japan.

30. Preparation and Properties of Monoclonal Antibody of SUN4599-resistant Tumor Cell. S. Yoshimura, M. Matsui, T. Nakanishi, T. Honda, and T. Noguchi; Forty-eighth Annual Meeting of the Japanese Cancer Association, (October, 1989), Nagoya, Japan.

31. Studies on Mechanism of Action of SUN4599. M. Matsui, S. Yoshimura, T. Nakanishi, T. Honda, T. Tsuruo, and T. Noguchi; Forty-eighth Annual Meeting of the Japanese Cancer Association, (October, 1989), Nagoya, Japan.

32. Antitumor Spectra of SUN4599 against Human Tumor Cells. J. Hashino, Y. Fukuda, T. Yoshida, T. Nakanishi, T. Honda, and T. Noguchi Forty-eighth Annual Meeting of the Japanese Cancer Association, (October, 1989), Nagoya, Japan.

33. A Novel Antitumor Agent. SUN4599, an Ellipticine Glycoside (1) -Antitumor Activity against Murine Tumors. S. Tsukagoshi, T. Tsuruo, T. Nakanishi, T. Honda, T. Noguchi, and K. Nitta Fifteenth International Cancer Congress, (August 16-22, 1990), Hamburg, Federal Republic of Germany.

34. A Novel Antitumor Agent. SUN4599, an Ellipticine Glycoside (2) -Effect against Human Tumor Cells. K. Nitta, S. Fujimoto, H. Tokita, T. Kunimoto, H. Baba, T. Nakanishi, T. Honda, T. Noguchi, and S. Tsukagoshi Fifteenth International Cancer Congress, (August 16-22, 1990), Hamburg, Federal Republic of Germany.

35. A Novel Antitumor Agent. SUN4599, an Ellipticine Glycoside (3) -Mechanism of Action. T. Tsuruo, K. Kunimoto, H. Baba, T. Nakanishi, T. Honda, T. Noguchi, S. Tsukagoshi, and K. Nitta Fifteenth International Cancer Congress, (August 16-22, 1990), Hamburg, Federal Republic of Germany.

36. Antitumor Effect of SUN4599 against Human Tumor Cells. J. Hashino, Y. Fukuda, T. Yoshida, T. Nakanishi, T. Honda, and T. Noguchi Forty-ninth Annual Meeting of the Japanese Cancer Association, (July, 1990), Sapporo, Japan.

37. Studies on Mechanism of Action of SUN4599. S. Yoshimura, M. Matsui, T. Nakanishi, T. Honda, T. Tsuruo, and T. Noguchi Forty-ninth Annual Meeting of the Japanese Cancer Association, (July, 1990), Sapporo, Japan.

38. Antitumor Activity of SUN4599 on Various Drug-resistant Tumor Cells. M. Matsui, S. Yoshimura, T. Nakanishi, T. Honda, and T. Noguchi Forty-ninth Annual Meeting of the Japanese Cancer Association, (July, 1990), Sapporo, Japan.

39. Direct Observation of Anticarcinoma Synergism Involving Fluorescent Cytotoxin Formation inside Tumor Cells. T. Honda, D. Rideout, T. McCracken, and J. Jaworski American Chemical Society Meeting, (April, 1991), Atlanta, USA .

40. Drug Delivery through Condensation of Two Prodrugs inside Tumor Cells: Direct Observation Using Fluorescence Microscopy. T. Honda, D. Rideout, M. McCarthy, T. McCracken, and J. Jaworski. Eighty-second Annual Meeting of the American Association for Cancer Research, (May 15-18, 1991), Houston, USA

41. Studies on Mechanism of Action of SUN4599. M. Matsui, S. Yoshimura, T. Nakanishi, T. Honda, T. Tsuruo, and T. Noguchi. Fiftieth Annual Meeting of the Japanese Cancer Association, (September, 1991), Tokyo, Japan.

42. Antineoplastic Drug Assembly from Two Prodrugs inside Carcinoma Cells: a New Approach to Experimental Combination Chemotherapy. J. Patel, D. Rideout, T. Honda, M. McCarthy, T. McCracken, T. Calogeropoulou, and J. Jaworski. American Chemical Society Meeting, (1991), USA.

43. Study of Triterpenoids as Cellular Differentiation Agents. Y. Wang, N. Suh, C. P. Williams, T. Honda, H. J. Finlay, G. W. Gribble, and M. B. Sporn. New England Pharmacologists 25th Annual Meeting, (1996), USA.

44. The Effect of A and C Ring Modification of Oleanolic and Ursolic Acid on the Inhibition of Nitric Oxide Formation in Mouse Macrophages H. J. Finlay, G. W. Gribble, T. Honda, N. Suh, and M. B. Sporn 213 th American Chemical Society National Meeting (April 13-17, 1997) San Francisco, USA

45. New Triterpenoids as Cancer Preventive and Anti-inflammatory Agents N. Suh, T. Honda, H. J. Finlay, A. Barchowsky, Q.-w. Xie, C. Nathan, G. W. Gribble, and M. B. Sporn. 88th Annual Meeting of the American Association for Cancer Research (April, 1997) San Diego, USA

46. New Synthetic Oleanane and Ursane Triterpenoids as Inhibitors of Nitric Oxide Production in Mouse Macrophages T. Honda, H. J. Finlay, N. Suh, M. B. Sporn, and G. W. Gribble. The Fifth Chemical Congress of North America (Nov. 11-15, 1997) Cancun, Mexico

47. 3a-OH Epimer of Ursolic Acid Inhibits Inducible cyclooxygenase (COX-2) in Colon Myofibroblasts Y. Wang, N. Suh, C. P. williams, T. Honda, H. J. Finlay, G. W. Gribble, and M. B. Sporn. New England Pharmacologists 27th Annual Meeting (Feb. 6-7, 1998) Boston, USA

48. Novel Triterpenoids Suppress Inducible Nitric Oxide Synthase (iNOS) and Inducible Cyclooxygenase (COX-2) N. Suh, C. P. Williams, Q. Xie, C. Nathan, T. Honda, H. J. Finlay, G. W. Gribble, and M. B. Sporn. 89th Annual Meeting of the American Association for Cancer Research (March 28-April 1, 1998) New Orleans, USA

49. A Novel Synthetic Oleanane Triterpenoid, 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic Acid (CDDO), Induces Cell Dtfferentiation in Human Myeloid Leukemias N. Suh, J. J. Letterio, A. E. Place, Y. Wang, C. R. Williams, L. Nguyen, T. Honda, G. W. Gribble, and M. B. Sporn. 90th Annual Meeting of the American Association for Cancer Research (April 10-14, 1999) Philadelphia, USA.

50. A Novel Synthetic Triterpenoid, 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic Acid (CDDO), Induces Adipocyte Differentiation in 3T3-L1 Cells Y. Wang, N. Suh, T. Honda, C. R. Williams, G. W. Gribble, and M. B. Sporn. 90th Annual Meeting of the American Association for Cancer Research (April 10-14, 1999) Philadelphia, USA.

51. Two Triterpenoids, CDDO and TP155C, are Potent Inducers of Apoptosis in Non-Small Cell Lung Cancer Cells. K. B. Kim, R. Lotan, P. Yue, M. B. Sporn, N. Suh, G. W. Gribble, T. Honda, W. K. Hong, and S. Y. Sun. The First International Chicago Symposium on Malignancies of the Chest and Head & Neck (1999) Chicago, IL, USA

52. CDDO, a Novel Synthetic Oleanane Triterpenoid, suppresses Nitric Oxide Production and Synthesis of Inducible Nitric Oxide Synthase (iNOS) in Female CD-1 Mice. N. Suh, Y. Wang, C. Williams, R. Risinsong, T. Honda, B. Rounds, L. Bore, G. W. Gribble, and M. B. Sporn. 91st Annual Meeting of the American Association for Cancer Research (April 1-5, 2000) San Francisco, CA, USA

53. A Synthetic Triterpenoid, 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic Acid (CDDO), is a Ligand for the Peroxisome Proliferator-Activated Receptor-g. Y. Wang, W. W. Porter, N. Suh, T. Honda, G. W. Gribble, D. J. Mangelsdorf, S. G. Blanchard, T. M. Wilson, and M. B. Sporn. 91st Annual Meeting of the American Association for Cancer Research (April 1-5, 2000) San Francisco, CA, USA

54. Effects of a Novel Triterpenoid, 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic Acid (CDDO), on Collagenase-3 (Matrix Metalloproteinase-13) Gene Expression. K. S. Mix, J. A. Mengshol, M. P. Vincenti, T. Honda, G. W. Gribble, M. B. Sporn, and C. E. Brinckerhoff. 91st Annual Meeting of the American Association for Cancer Research (April 1-5, 2000) San Francisco, CA, USA

55. Caspase-3 Activation is involved in Apoptosis induced by a Synthetic Triterpenoid in Non-Small Cell Lung Cancer (NSCLC) Cells. K. B. S. Kim, R. Lotan, P. Yue, M. B. Sporn, N. Suh, G. W. Gribble, T. Honda, W. K. Hong, and S. Y. Sun. 91st Annual Meeting of the American Association for Cancer Research (April 1-5, 2000) San Francisco, CA, USA

56. New Triterpenoids for Prevention of Breast Cancer. N. Suh, Y. Wang, C. Williams, R. Risingsong, T. Honda, L. Bore, G. W. Gribble, and M. B. Sporn DOD Breast Cancer Research Program, Era of Hope (June 8-12, 2000), Atlanta, GA

57. Novel Synthetic Oleanane and Ursane Triterpenoids with Various Enone Functionalities in Ring A as Inhibitors of Nitric Oxide Production in Mouse Macrophages. T. Honda, G. W. Gribble, N. Suh, H. J. Finlay, B. V. Rounds, L. Bore, F. G. Favaloro Jr, Y. Wang, and M. B. Sporn. 220th American Chemical Society National Meeting (August 20-24, 2000) Washington, DC, USA

58. Novel Synthetic Oleanane and Ursane Triterpenoids with Ring A and C Modifications: A Series of Highly Active Inhibitors of Nitric Oxide Production in Mouse Macrophages. T. Honda, G. W. Gribble, B. V. Rounds, N. Suh, H. J. Finlay, L. Bore, F. G. Favaloro Jr, Y. Wang, and M. B. Sporn. 220th American Chemical Society National Meeting (August 20-24, 2000) Washington, DC, USA

59. Novel Synthetic Oleanane and Ursane Triterpenoids with Enone Functionalities in Rings A and C: A Series of Highly Active Inhibitors of Nitric Oxide Production in Mouse Macrophages. T. Honda, G. W. Gribble, B. V. Rounds, N. Suh, H. J. Finlay, L. Bore, F. G. Favaloro Jr, Y. Wang, and M. B. Sporn 2000 International Chemical Congress of Pacific Basin Societies (December 14-19, 2000) Honolulu, HI, USA

60. Synthetic Triterpenoids Induce Differentiation of Human Leukemia Cells and Reduce tumor Burden in Murine Cancer Models. E. A. Place, N. Suh, M. Rendi, C. Williams, R. Risingsong, T. Honda, G. Gribble, and M. Sporn, M. 93rd Annual Meeting of the American Association for Cancer Research (April 6–10, 2002), San Francisco, CA, USA

61. Synthetic Triterpenoids Derived from Naturally Occurring Molecules. M. B. Sporn, N. Suh, A. E. Place, G. W. Gribble, T. Honda, and Y. Honda. 224th American Chemical Society National Meeting (August 18–22, 2002) Boston, MA, USA

62. Design and Synthesis of Tricyclic Compounds with Enone Functionalities in Rings A and C: A Novel Class of Highly Active Inhibitors of Nitric Oxide Production in Mouse Macrophages. T. Honda, F. G. Favaloro, Jr., Y. Honda, G. W. Gribble, N. Suh, R. Risingsong, and M. B. Sporn. 225th American Chemical Society National Meeting (March 23–27, 2003) New Orleans, LA, USA

63. Synthetic Triterpenoids Suppress Inflammation in the Gastrointestinal Tract: Mechanics of Interaction of CDDO and CDDO-Imidazolide with Interferon-g, TGF-b, and Smad Signaling. E. H. Heiss, L. A. Minns, N. Suh, D. Buzoni-Gatel, L. H. Kasper, G. W. Gribble, T. Honda, and M. B. Sporn,. 94th Annual Meeting of the American Association for Cancer Research (July 11–14, 2003), Washington, DC, USA


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