Publication List          

Publications Currently in Press (2004)       2004 Publications       2003 Publications       2002 Publications

Book Chapters Currently in Press (2004)       2003 Book Chapters

Publications Currently in Press (2004)

Alam, T.M., Celina, M., Collier, J.P., Currier, B.H., Currier, J.H., Jackson, S.K., Kuethe, D.O. and Timmins, G.S. (2004). “*g-Irradiation of UHMWPE- EPR and NMR Spectroscopic and Imaging Studies of the Mechanism of Sub-Surface Oxidation, J. of the American Chem. Soc. In Press. 

Charlier, N., Beghein, N. and Gallez, B. (2004). “Development and Evaluation of Biocompatible Inks for the Local Measurement of Oxygen Using In Vivo EPR,” NMR Biomed. In Press. 

Gallez, B., Baudelet, C., and Jordon, B.F. (2004). “Assessment of Tumor Oxygenation by EPR Oximetry: Principles and Applications,” NMR Biomed. In Press 

Grinberg, V.O., Smirnov, A.I., Grinberg, O.Y., Grinberg, S.A., O’Hara, J.A. and Swartz, H.M. (2004). “Practical Conditions and Limitations for High Spatial Resolution Multi-Site EPR Oximetry,” Appl. Magn. Reson.  In Press. 

Harold M. Swartz, Nadeem Khan, Jay Buckey, Richard Comi, Lisa Gould, Oleg Grinberg, Alan Hartford, Harriet Hopf, Huagang Hou, Eugen Hug, Akinori Iwasaki, Piotr Lesniewski, Ildar Salikhov and Tadeusz Walczak, NMR in Biomed. 2004; 17, 1-17. "Clinical applications of EPR: overview & perspectives".

Hou, H., Grinberg, O.Y., Grinberg, S.A., Khan, N., Dunn, J.F. and Swartz, H.M. (2004). “Cerebral PtO2, Actute Hypoxic Hypoxia, and Volatile Anesthetics in the Rat Brain,” Oxygen Transport to Tissue (Okunieff, P. ed). Plenum Publishers, New York.  In Press. 

Iwasaki, A., Grinberg, O., Walczak, T., and Swartz, H.M. (2004). “In Vivo Measurements of EPR Signals in Whole Human Teeth,” Applied Radiation and Isotopes.  In Press. 

Iwasaki, A., Walczak, T., Grinberg, O., and Swartz, H.M. (2004). “Differentiation of the Observed Low Frequency (1200 MHz) EPR  Signals in Whole Human Teeth,” Applied Radiation and Isotopes. In Press. 

Khan, N., Hou, H., Hein, P., Comi, R.J., Buckey, J.C., Grinberg, O., Salikhov, I., Lu, S.Y., Wallach, H. and Swartz, H.M. (2004). “Black Magic and EPR Oximetry: From Lab to Initial Clinical Trials,” Oxygen Transport to Tissue (Okunieff, P. ed). Plenum Publishers, New York.  In Press. 

Liu, S., Timmins, GS., Shi, H., Gasparovic, C.M., and Liu, K.J. (2004). “Application of In Vivo EPR in Brain Research: Monitoring Tissue Oxygenation, Blood Flow, and Oxidative Stress,” NMR in Biomedicine. In Press. 

Romanyukha, A.A., Ivanov, D., Schauer, D.A., Thomas, J.A. and Swartz, H.M. (2004). “Spectrum File Size Optimization for EPR Tooth Dosimetry,” Applied Radiation and Isotopes. In Press. 

Sakata, Y.S., Grinberg, O.Y., Grinberg, S., Springett, R. and Swartz, H.M. (2004). “Simultaneous NIR-EPR Spectroscopy of Rat Brain Oxygenation,” Oxygen Transport to Tissue (Okunieff, P. ed). Plenum Publishers, New York.  In Press. 

Schauer, D.A., Iwasaki, A., Romanyukha, A., Swartz, H.M. and Onori, S. (2004). “Electron Paramagnetic Resonance (EPR) in Medical Dosimetry,” Radiation Measurements. In Press 

Schauer, D.A., Romanyukha, A., Thomas, J.A., Romanyukha, L., Iwasaki, A., and Swartz, H.M. (2004). “Enhanced EPR Dose Reconstruction in Teeth,” 11th International Congress of the International Radiation Protection Association, Proceedings, In Press. 

Swartz, H.M. (2004). “Using EPR to Measure a Critical but Often Unmeasured Component of Oxidative Damage:  Oxygen,” Antioxidant & Redox Signaling Journal. In Press. 

Swartz, H.M., Iwasaki, A., Walczak, T., Demidenko, E., Salikhov, I., Lesniewski, P., Starewicz, P. and Romanyukha, A. (2004). “Measurements of Clinically Significant Doses of Ionizing Radiation Using Non-Invasive In Vivo EPR Spectroscopy of Teeth In Situ,” Applied Radiation and Isotopes. In Press. 

Swartz, H.M. and Dunn, J. (2004). “The Difficulties in Comparing In Vivo Oxygen Measurements – Turning the Problems into Benefits,” Oxygen Transport to Tissue (Okunieff, P. ed). Plenum Publishers, New York.  In Press. 

Takeshita, K., Takajo, T., Hirata, H., Ono, M. and Utsumi, H. (2004). “In Vivo Evidence of Oxygen Radical Generation inSkin of Protoporphyria Model Mouse Under Visible Light Exposure: An L-Band Electron Spin Resonance Study with a Surface-Coil-Type Resonator,” J. of Investigative Dermatology. In Press.

2004 Publications

Grinberg, O. Y., H. Hou, et al. (2004). "pO2 and regional blood flow in a rabbit model of limb ischemia." Physiol Meas 25(3): 659-70. 

Hirata, H., T. Kuyama, et al. (2004). "Nonequivalent spectra of unpaired electrons in field and frequency modulation." J Magn Reson 168(2): 252-8. 

Hou, H., N. Khan, et al. (2004). "Effect of RSR13, an allosteric hemoglobin modifier, on oxygenation in murine tumors: an in vivo electron paramagnetic resonance oximetry and bold MRI study." Int J Radiat Oncol Biol Phys 59(3): 834-43. 

Liu, S., H. Shi, et al. (2004). "Interstitial pO2 in ischemic penumbra and core are differentially affected following transient focal cerebral ischemia in rats." J Cereb Blood Flow Metab 24(3): 343-9. 

Jackson, S.K., Thomas, M.J., Smith, S., Madhani, M., Rogers, S.C. and James, P.E. (2004). “In Vivo EPR Spectroscopy: Biomedical and Potential Diagnostic Applications,” Faraday Discussions 126:103-17; discussion 169-93. 

Petelin, M., Z. Pavlica, et al. (2004). "In vivo study of different ointments for drug delivery into oral mucosa by EPR oximetry." Int J Pharm 270(1-2): 83-91. 

Sentjurc, M., M. Cemazar, et al. (2004). "EPR oximetry of tumors in vivo in cancer therapy." Spectrochim Acta A Mol Biomol Spectrosc 60(6): 1379-85. 

Sentjurc, M., J. Kristl, et al. (2004). "Transport of liposome-entrapped substances into skin as measured by electron paramagnetic resonance oximetry in vivo." Methods Enzymol 387: 267-87. 

Swartz, H. M. (2004). "Using EPR to measure a critical but often unmeasured component of oxidative damage: oxygen." Antioxid Redox Signal 6(3): 677-86.

2003 Publications

Chen, B., B. W. Pogue, et al. (2003). "Blood flow dynamics after photodynamic therapy with verteporfin in the RIF-1 tumor." Radiat Res 160(4): 452-9. 

Dunn, J. F. and H. M. Swartz (2003). "In vivo electron paramagnetic resonance oximetry with particulate materials." Methods 30(2): 159-66. 

Grinberg, O. Y., M. Miyake, et al. (2003). "The dose-dependent effect of RSR13, a synthetic allosteric modifier of hemoglobin, on physiological parameters and brain tissue oxygenation in rats." Adv Exp Med Biol 530: 287-96. 

Hirata, H., Y. Yamaguchi, et al. (2003). "Control characteristics of an automatic matching control system for in vivo EPR spectroscopy." Magn Reson Med 50(1): 223-7. 

Hou, H., O. Y. Grinberg, et al. (2003). "Electron paramagnetic resonance assessment of brain tissue oxygen tension in anesthetized rats." Anesth Analg 96(5): 1467-72, table of contents. 

James, P. E., M. Madhani, et al. (2003). "Tissue hypoxia during bacterial sepsis is attenuated by PR-39, an antibacterial peptide." Adv Exp Med Biol 530: 645-52. 

Khan, N., J. Shen, et al. (2003). "Plasma membrane cholesterol: a possible barrier to intracellular oxygen in normal and mutant CHO cells defective in cholesterol metabolism." Biochemistry 42(1): 23-9. 

Khan, N., C. M. Wilmot, et al. (2003). "Spin traps: in vitro toxicity and stability of radical adducts." Free Radic Biol Med 34(11): 1473-81. 

Kristl, J., Z. Abramovic, et al. (2003). "Skin oxygenation after topical application of liposome-entrapped benzyl nicotinate as measured by EPR oximetry in vivo: influence of composition and size." AAPS PharmSci 5(1): E2. 

Miyake, M., O. Y. Grinberg, et al. (2003). "The effect of RSR13, a synthetic allosteric modifier of hemoglobin, on brain tissue pO2 (measured by EPR oximetry) following severe hemorrhagic shock in rats." Adv Exp Med Biol 530: 319-29. 

Nwaigwe, C. I., M. A. Roche, et al. (2003). "Brain tissue and sagittal sinus pO2 measurements using the lifetimes of oxygen-quenched luminescence of a ruthenium compound." Adv Exp Med Biol 530: 101-11. 

O'Hara, J. A., R. D. Blumenthal, et al. (2003). "Tumor pO2 assessments in human xenograft tumors measured by EPR oximetry: location of paramagnetic materials." Adv Exp Med Biol 530: 205-14. 

Pogue, B. W., J. A. O'Hara, et al. (2003). "Photodynamic therapy with verteporfin in the radiation-induced fibrosarcoma-1 tumor causes enhanced radiation sensitivity." Cancer Res 63(5): 1025-33. 

Salikhov, I., H. Hirata, et al. (2003). "An improved external loop resonator for in vivo L-band EPR spectroscopy." J Magn Reson 164(1): 54-9. 

Shen, J., N. Khan, et al. (2003). "Oxygen consumption rates and oxygen concentration in molt-4 cells and their mtDNA depleted (rho0) mutants." Biophys J 84(2 Pt 1): 1291-8. 

Shen, J.G., Fung, P.C.W., and Swartz, H.M. (2003). “Electon Paramagnetic Resonance (EPR) Oximetry: A Novel Opportunity for Monitoring Tissue and Cellular Oxygen Concentration in Biological Systems In Vivo and In Vitro,” Hong Kong Medical Journal 9(suppl.): 40. 

Swartz, H. M. and J. F. Dunn (2003). "Measurements of oxygen in tissues: overview and perspectives on methods." Adv Exp Med Biol 530: 1-12. 

Swartz, H. M., S. Taie, et al. (2003). "The effects of anesthesia on cerebral tissue oxygen tension: use of EPR oximetry to make repeated measurements." Adv Exp Med Biol 530: 569-75. 

Zdravkova, M., N. Crokart, et al. (2003). "Retrospective dosimetry after criticality accidents using low-frequency EPR: a study of whole human teeth irradiated in a mixed neutron and gamma-radiation field." Radiat Res 160(2): 168-73. 

Zdravkova, M., Wieser, A., El-Faranawy, N., Ivanov, D., Gallez, B. and Debuyst, R. (2003). “An In Vitro L-Band EPR Study with Whole Human Teeth in a Surface Coil Resonator,” Radiat. Meas. 37:347-353. 

2002 Publications 

Cevc, P., Walczak, T., and Swartz, H.M., (2002) “Whole Body L-Band Resonator with a Wide Range Frequency Tuning Using Piezo Actuator,” Current Topics in Biophysics 26:15-19. 

Dunn, J. F., J. A. O'Hara, et al. (2002). "Changes in oxygenation of intracranial tumors with carbogen: a BOLD MRI and EPR oximetry study." J Magn Reson Imaging 16(5): 511-21. 

Gallez, B. and N. Beghein (2002). "Noninvasive in vivo EPR monitoring of the methyl methacrylate polymerization during the bone cement formation." Biomaterials 23(24): 4701-4. 

Jackson, S. K., K. J. Liu, et al. (2002). "Detection and removal of contaminating hydroxylamines from the spin trap DEPMPO, and re-evaluation of its use to indicate nitrone radical cation formation and S(N)1 reactions." Free Radic Biol Med 32(3): 228-32. 

James, P. E., M. Madhani, et al. (2002). "Endotoxin-induced liver hypoxia: defective oxygen delivery versus oxygen consumption." Nitric Oxide 6(1): 18-28. 

James, P. E. and H. M. Swartz (2002). "Simultaneous detection of pO2 and NO by electron paramagnetic resonance." Methods Enzymol 359: 52-66. 

Khan, N. and H. Swartz (2002). "Measurements in vivo of parameters pertinent to ROS/RNS using EPR spectroscopy." Mol Cell Biochem 234-235(1-2): 341-57. 

Liu, M., S. Liu, et al. (2002). "On the application of 4-hydroxybenzoic acid as a trapping agent to study hydroxyl radical generation during cerebral ischemia and reperfusion." Mol Cell Biochem 234-235(1-2): 379-85. 

Madhani, M., A. Barchowsky, et al. (2002). "Antibacterial peptide PR-39 affects local nitric oxide and preserves tissue oxygenation in the liver during septic shock." Biochim Biophys Acta 1588(3): 232-40. 

Pogue, B. W., J. A. O'Hara, et al. (2002). "Tumor PO(2) changes during photodynamic therapy depend upon photosensitizer type and time after injection." Comp Biochem Physiol A Mol Integr Physiol 132(1): 177-84. 

Sentjurc, M. (2002). "Blood flow enhancement in skin or oral mucosa after the topical application of liposome entrapped rubifacient as measured by EPR oximetry in vivo: the influence of size and liposome composition." Cell Mol Biol Lett 7(2): 256-8. 

Sersa, G., M. Krzic, et al. (2002). "Reduced blood flow and oxygenation in SA-1 tumours after electrochemotherapy with cisplatin." Br J Cancer 87(9): 1047-54. 

Shen, J., Bottle, S., Khan, N., Grinberg, O., Reid, D., Micallef, A. and Swartz, H.M. (2002). “Development of Isoindoline Nitroxides for EPR Oximetry in Viable Systems,” Appl. Magn. Reson. 22:357-368. 

Shen, J.G., Khan, N., Chang, T.Y., Fung, P.C.W., Grinberg, O., and Swartz, H.M. (2002). “Plasma Membrane Cholesterol is a Key Molecule in Formation of Intracellular Oxygen Gradients in CHO Cells,” The Hong Kong Practitioner Journal of Hong Kong College of Family Physicians 24: 13. 

Swartz, H. M. (2002). "Measuring real levels of oxygen in vivo: opportunities and challenges." Biochem Soc Trans 30(2): 248-52. 

Thomas, M.P., Jackson, S.K., James, P.E. (2002). “Variation in Blood Oxygenation and Cerebral pO2 in a Mouse Model Measured by EPR Spectroscopy,” Adv. Exp. Med. Biol. 510:205-211 (Wilson, D.F., ed.), Plenum Publishing, New York. 

Towner, R. A., S. A. Sturgeon, et al. (2002). "In vivo assessment of nodularin-induced hepatotoxicity in the rat using magnetic resonance techniques (MRI, MRS and EPR oximetry)." Chem Biol Interact 139(3): 231-50. 

Zdravkova, M., J. M. Denis, et al. (2002). "Sensitivity of whole human teeth to fast neutrons and gamma-rays estimated by L-band EPR spectroscopy." Radiat Meas 35(6): 603-8. 

Zdravkova, M., A. Wieser, et al. (2002). "An in vitro L-band electron paramagnetic resonance study of highly irradiated whole teeth." Radiat Prot Dosimetry 101(1-4): 497-502.

Book Chapters Currently in Press (2004)

Grinberg, O., Hou, H., Roche, M.A., Merlis, J., Grinberg, S.A., Khan, N., Swartz, H.M. and Dunn, J.F., “Modeling of the Response of ptO2 in Rat Brain to Changes in Physiological Parameters,” Oxygen Transport to Tissue (Okunieff, P. ed). Plenum Publishers, New York.  In Press (2004). 

Grinberg, O., Novozhilov, B., Grinberg, S., Friedman, B. and Swartz, H.M., “Axial Oxygen Diffusion in the Krogh Model: Modifications to Account for Myocardial Oxygen Tension in Isolated Perfused Rat Hearts Measured by EPR Oximetry,” Oxygen Transport to Tissue (Okunieff, P., ed.) Plenum Publishers, New York. In Press (2004). 

Subczynski, W.K. and H.M. Swartz, H.M., “EPR Oximetry in Biological and Model Samples,” in Biomedical ESR a volume in the Biological Magnetic Resonance Series (S.S. Eaton, G.R. Eaton, L.J. Berliner, eds.), Kluwer Publisher (The Netherlands, New York, Boston), Chapter 10, pp 229-282. In Press (2004). 

Swartz, H.M., “An Incomplete History of Jim Hyde and the EPR Center at MCW,” in Biomedical ESR, a volume in the Biological Magnetic Resonance Series (S.S. Eaton, G.R. Eaton, L.J. Berliner, eds.), Kluwer Publisher (The Netherlands, New York, Boston), Chapter 2, pp 7-22. In Press (2004). 

Swartz, H.M. and Khan, N., “EPR Spectroscopy Of Function In Vivo: Origins, Achievements, And Future Possibilities,” in Biomedical ESR a volume in the Biological Magnetic Resonance Series (S.S. Eaton, G.R. Eaton, L.J. Berliner, eds.), Kluwer Publisher (The Netherlands, New York, Boston), Chapter 9, pp 197-228. In Press (2004). 

Swartz, H.M., Mason, R.P., Hogg, N., Kalyanaraman, B., Sarna, T., Plonka, P.M. Zareb, M., Gutierrez, P.L and Berliner, L.J., “Free Radicals and Medicine,” ,” in Biomedical ESR a volume in the Biological Magnetic Resonance Series (S.S. Eaton, G.R. Eaton, L.J. Berliner, eds.), Kluwer Publisher (The Netherlands, New York, Boston), Chapter 3, pp. 25-74, In Press (2004).

2003 Book Chapters

Berliner, L. and Swartz, H.M., “Introduction to In Vivo EPR,” in Biological Magnetic Resonance: Volume 18 in Vivo EPR (ESR): Theory and Applications (Book). L.J. Berliner (ed.), Plenum Publishing Company, New York. pp 1-21 (2003).   

Dunn, J.F. and Swartz, H.M., “Combining NMR and EPR/ESR for In Vivo Experiments,” in Biological Magnetic Resonance - Volume 18: In Vivo EPR (ESR): Theory and Applications (Book). L.J. Berliner (ed.), Plenum Publishing Co., NY. pp 579-597 (2003). 

Gallez, B., “Packaging of Stable Paramagnetic Oxygen-Sensors,” in: In Vivo EPR (ESR). Biological Magnetic Resonance, Volume 18, L. Berliner, ed., pp. 259-284 (2003). 

Mäder, K. and Gallez, B., “Pharmaceutical Applications of In Vivo EPR,” In: Biological Magnetic Resonance, Volume 18 In Vivo EPR (ESR): Theory and Applications (Book). L. J. Berliner (ed.), Plenum Publishing Company, New York, pp 515-545 (2003). 

Swartz, H.M., "Potential Medical (Clinical!!!) Applications of EPR: Overview & Perspectives," in Biological Magnetic Resonance - Volume 18: In Vivo EPR (ESR): Theory and Applications (Book). L.J. Berliner (ed.), Plenum Publishing Co. NY,  pp 600-621(2003). 

Swartz, H.M., “The Measurement of Oxygen In Vivo Using EPR Techniques,” in Biological Magnetic Resonance - Volume 18: In Vivo EPR (ESR): Theory and Applications (Book). L.J. Berliner (ed.), Plenum Publishing Co., NY, pp 403-440 (2003) 

Timmins, G.S. and Liu, K.J., “Spin Trapping: Facts and Artifacts”, in Biological Magnetic Resonance - Volume 18: In Vivo EPR (ESR): Theory and Applications (Book). L.J. Berliner (ed.), Plenum Publishing Co., NY. pp. 285-308 (2003).

home