Charles K. Barlowe
Departments: Biochemistry
First name: Charles
Middle name: Kimbrough
Last name: Barlowe
Email: barlowe@dartmouth.edu
Phone: 603 650-6516
Office: 414 Remsen
Titles:
Professor of Biochemistry
Dean of Graduate Studies
Education: B.S. College of William & Mary; Ph.D. University of Texas at Austin
Areas of expertise:Biochemical mechanisms of coated vesicle formation; Membrane fusion; Intracellular transport; Cell biology
Selected works:
- Bue, C A, C M Bentivoglio, and C Barlowe, “Erv26p Directs Pro-alkaline Phosphatase into ER-derived COPII Transport Vesicles,†Molecular Biology of the Cell, 17 (2006) 4780-4789.
- Wilson, J D, Y Liu, C M Bentivoglio, and C Barlowe, “Sel1p/Ubx2p Participates in a Distinct Cdc48p-dependent ERAD Pathway,†Traffic, 7 (2006) 1213-1223.
- Flanagan, J J, and C Barlowe, “Cysteine-disulfide Cross-linking to Monitor SNARE Complex Assembly during Endoplasmic Reticulum-Golgi Transport,†Journal of Biological Chemistry, 281 (2006) 2281-2288.
- Heidtman, M, C Z Chen, R N Collins, and C Barlowe, “Yos1p is a Novel Subunit of the Yip1p-Yif1p Complex and is Required for Transport between the ER and the Golgi Complex,†Molecular Biology of the Cell, 16 (2005) 1673-1683.
- Otte, S, and C Barlowe, “Sorting Signals Can Direct Receptor-mediated Export of Soluble Proteins into COPII Vesicles,†Nature Cell Biology, 6 (2004) 1189-1194.
Current projects: “Mechanisms of COPII-dependent transport;†"Role of specific lipid species in the early secretory pathway;†“ER quality control mechanismsâ€
Related Links:
http://dms.dartmouth.edu/barlowe