Using Amberlyst A-15. To 0.7 g of Amberlyst A-15 in a 25 mL rb flask was added a solution of 0.12 mL (1mmole) of 1-methylcyclohexanol in 1.5 mL of methyl tertiary butyl ether (MTBE). The flask was placed on a rotary evaporator and heated gently until no liquid MTBE was evident and the A-15 was a free flowing powder. The resin-supported 1-methylcyclohexanol was transferred to an 8 mL SPE reservior and placed in a small beaker into the microwave oven. The heating protocol used was heat 10 sec, cool 3 min (repeat 5 times), heat 10 sec, cool 1 min (repeat 6 times) for a total heating time of 2 min and 10 sec. The protocol kept the temperature between 40 and 70 degrees C. After the last cooling the tube was gravity eluted with 1 mL of MTBE and analyzed by G.C.
These experiments are designed to be used in college and university level chemistry laboratory courses, and assume the availability of routine supplies, equipment, and instrumentation usually associated with organic chemistry laboratory courses, as well as an appropriate modern level of supervision, safety training, personal protective equipment, and other safety facilities. Any users of these procedures assume all responsibility for the safe handling of hazardous chemicals and procedures. In any event the authors, webmasters, The University of Wyoming , Rochester Institute of Technology, or Dartmouth College shall not be liable for incidental or consequential damages in connection with, or arising out of, the furnishing, performance, or use of these procedures.