Professor Aprahamian received all his degrees (BSc in 1998, MS in 2000, and PhD in 2005) from the Hebrew University of Jerusalem, Israel. His doctoral research was conducted under the supervision of Professors Mordecai Rabinovitz and Tuvia Sheradsky and focused on NMR spectroscopic studies of alkali metal reduced polycyclic aromatic hydrocarbons. He then carried out postdoctoral research in Professor J Fraser Stoddart's Group at UCLA, where he focused on the synthesis of switchable and highly-ordered interlocked molecules in the form of bistable [n]rotaxanes. Dr. Aprahamian joined the faculty at Dartmouth College in August 2008.
Our interest in controlling molecular motion and converting it into mechanical work has driven us to the development of new hydrazone-based molecular switches that can be activated either chemically or photochemically. These novel systems are expected to form the basis of various molecular machines and motors.
The group is also developing new hydrazone-based fluorophores (i.e., solid-state BODIHY dyes, and blue-light emitting Triazolopyridinium salts) that can be used in sensing, bio-imaging, and OLED applications, among others.
* X. Su, S. Voskian, R. P. Hughes, I. Aprahamian*, "Manipulating liquid crystal properties using a pH activated hydrazone switch", Angew. Chem. Int. Ed. 2013, 52, 10734–10739.
* T. F. Robbins, H. Qian, X. Su, R. P. Hughes, I. Aprahamian*, "Cyanide detection using a triazolopyridinium salt", Org. Lett. 2013, 15, 2386–2389.
* X. Su, M. Liptak, I. Aprahamian*, "Water soluble triazolopyridinium salts as tunable blue light emitters", Chem. Commun. 2013, 49, 4160–4162.
Invited contribution to the 2013 ChemComm Emerging Investigator Issue.
* Y. Yang, R. P. Hughes, I. Aprahamian*, "Visible light switching of a BF2-coordinated azo compound", J. Am. Chem. Soc. 2012, 134, 15221–15224.
Highlighted in Chemistry & Engineering News (September 17, 2012, p26).
* X. Su, M. Lókov, A. Kütt, I. Leito*, I. Aprahamian*, "Unusual para-substituent effects on the intramolecular hydrogen-bond in hydrazone-based switches", Chem. Commun. 2012, 48, 10490-10492.
Invited contribution to the special issue on Aromaticity.
* D. Ray, J. T. Foy, R. P. Hughes, I. Aprahamian*, "A switching cascade of hydrazone-based rotary switches through coordination-coupled proton relays", Nature Chem. 2012, 4,757-762.
Highlighted in the News and Views section of Nature Chemistry (2012, 4, 695-696).
Last Updated: 12/3/13