Coronary Artery Disease Trials

MAGIC Trial

Name of Trial: MAGIC – Monocyte Response to Hypoxia and Genetic Background in Patients with and Without Coronary Collateral Circulation

CPHS #: 15622

Start Date: 2002

End Date: 2007

Description of Trial: The purpose of this study is to obtain blood donations from patients who are going to have a cardiac catheterization.

• The study look at the cath lab films and make comparisons between patients who have this collateral blood vessel development and those who do not.
• The study will look for differences in monocytes (cells in your body) which have been shown to stimulate production growth factors involved in new blood vessel growth.
• The study will look at differences in genetic markers between the two groups (those who have collateral circulation and those who don’t).

For more information on research at the Dartmouth-Hitchcock Medical Center, please visit either the DHMC Clinical Trials site or the Dartmouth Medical School Research page.