Fellow Projects:
The following is a partial list of onging research projects by current DHMC cardiology fellows:
Mandeep Sidhu:
1) Real World, Long-term Outcomes Comparison Between Paclitaxel-Eluting and
Sirolimus-Eluting Stent Platforms
Mandeep S. Sidhu, M.D., M.B.A.,1 Jeremiah R. Brown, PhD,2 Rayson C. Yang M.D., 1
James T. DeVries, M.D.,1 John E. Jayne, M.D.,1 Bruce D. Hettleman, M.D.,1 Bruce J.
Friedman, M.D.,1 Nathaniel W. Niles, M.D.,1 Aaron V. Kaplan, M.D.,1 John F. Robb,
M.D. ,1 David J. Malenka, M.D. 1, and Craig A. Thompson, M.D., M.M.Sc.2 for the
Dartmouth Dynamic Registry Investigators
2) Reigel v. Medtronic: The Supreme Court upholds pre-emption associated with the
Medical Device Act regarding PMA Devices. Good policy or loss of an important safe
guard? William H. Maisel, M.D., M.P.H., Paul LaViolette, M.B.A., Beverly H. Lorell, M.D.,
Mandeep S. Sidhu, M.D., M.B.A., Aaron V. Kaplan, M.D.
3) Pre-Market Approval (PMA): The Approval Path for High Risk Medical Devices. 30 year Perspective after the Medical Device Amendments Act of 1976.
Mandeep S. Sidhu, M.D., M.B.A., Aaron V. Kaplan, M.D.
4) Classification and Atherosclersosis Distribution in Patients with Left Main Coronary
Disease Craig A. Thompson, M.D.,a MMSc., Mandeep S. Sidhu, M.D., M.B.A.,a Jeremiah R. Brown, Ph.D.,a,b Sajjad A. Sabir, M.D.,a Kevin C. Floyd, M.D.,a James T. De Vries M.D.,a John E. Jayne, M.D.,a Bruce J. Friedman, M.D.,a Bruce D. Hettleman, M.D.,a Nathaniel W. Niles, M.D.,a John F. Robb, M.D.,a David J. Malenka, M.D.,a and Aaron V. Kaplan, M.D.a for the Dartmouth Dynamic Registry Investigators
5) The Impact of Hematocrit Drop on Long Term Survival after Cardiac Catheterization: Insights from the Dartmouth Dynamic Registry Calvin C. Leung, M.D.,1 Sajjad A. Sabir, M.D.,1 Jeremiah R. Brown, Ph.D.,2 Mandeep
S. Sidhu, M.D.M.B.A,3 Aaron V. Kaplan, M.D.,3 John E. Jayne, M.D.,3 Bruce J.
Friedman, M.D.,3 Bruce D. Hettleman, M.D.,3 Nathaniel W. Niles, M.D.,3 James T.
DeVries, M.D.,3 John F. Robb, M.D.,3 David J. Malenka, M. D., 3 and Craig A.
Thompson, M.D., MMSc;3 for the Dartmouth Dynamic Registry Investigators
6) The Evaluation of Creatinine Clearance, Estimated Glomerular Filtration Rate, and
Serum Creatinine in Predicting Contrast-induced Acute Kidney Injury Among Patients
Undergoing Percutaneous Coronary Intervention. Alina M. Robert, MD; Jeremiah R. Brown, PhD; Mandeep S. Sidhu, MD, MBA; Vijay S. Ramanath, MD; James T. DeVries, MD; John E. Jayne, MD; Bruce D. Hettleman, MD; Bruce J. Friedman, MD; Nathaniel W. Niles II, MD; Aaron V. Kaplan, MD; John F. Robb, MD; David J. Malenka, MD; Craig A. Thompson, MD, MMSc The Dartmouth Dynamic Registry
7) Outcomes of Diabetics and Non-diabetics Receiving Bare-Metal Stents versus Drug
Eluting Stents Vijay S. Ramanath, MD; Jeremiah R. Brown, PhD; Mandeep S. Sidhu, MD, MBA; Alina M. Robert, MD; James T. DeVries, MD; John E. Jayne, MD; Bruce D. Hettleman, MD; Bruce J. Friedman, MD; Nathaniel W. Niles II, MD; Aaron V. Kaplan, MD; John F. Robb, MD; David J. Malenka, MD; Craig A. Thompson, MD, MMSc The Dartmouth Dynamic Registry
8) Drug Eluting Stent Reduction in Target Vessel Revascularization Extends Beyond
On-Label Usage Kevin Desrosiers, MD1; Mandeep Sidhu, MD, MBA1; Jeremiah Brown, PhD2, Craig A. Thompson, MD, M.M.Sc.2; and David J. Malenka, MD1
Pantila Vanichakarn:
2008-present Angiogenesis Center, Dartmouth College, Dr. John Hwa; Study
how genetic polymorphisms (DNA sequences of prostacyclin and thromboxane
receptors) may be associated with one’s risk for development of coronary
artery disease.
2008-present Dartmouth Hitchcock Medical Center, Dr. Nathaniel Niles; ST
elevation MI (STEMI) registry; Analyze the current data from the STEMI
registry to evaluate for efficacy and efficiency of the management of
patients with ST elevation MI and to try to improve care to enhance
outcome of these patients in the future.
Jason Foerst:
MicroCT Evaluation of Stented Human Carotid and Coronary Arterial Segments
Presented at DHMC Cardiology Grand Rounds
Mentor: Aaron Kaplan, MD
Vaibhav Moondra:
1. Safety and Efficacy of placement of Fidelis ICD lead in non-apical sites. Manuscript in progress.
2. Case presentation: Spontaneous deterioration of typical AVNRT to polymorphic VT in a patient with out structural heart disease. Manuscript in progress.
3. Prevalence and potential risk factors for development of pulmonary hypertension in patients withheart failure with preserved systolic function. Manuscript in progress.
4. Single center experience of use of autonomic blockade during electrophysiologic testing in patients with syncope of unknown origin. Data review in progress
5. Development of blood bank of samples of all patients referred to Electrophysiology laboratory for ablations, device placement and EP study. Collect samples from various EP populations (i.e. “lone” atrial fibrillation) and maintain a database of patient and EP study characteristics. Ultimate goal is to identify genetic mutations that may be associated with question of interest and develop model to understand how the abnormality translates to the pathologic state.
Carl Musser:
"Frequency content analysis of ventricular fibrillation during defibrillation
threshold testing"
Advisor: Rajbir Sangha, Dartmouth-Hitchcock Medical Center
"The use of a non-apical fixation site may decrease the Sprint Fidelis lead fracture
rate"
Advisor: Rajbir Sangha, Dartmouth-Hitchcock Medical Center
Abstract submitted to Heart Rhythm Society 2009 Annual Scientific Sessions.
"Real-time transthoracic three-dimensional echocardiography is superior to
two-dimensional echocardiography for pulmonary vein identification"
Advisor: Robert Palac, Dartmouth-Hitchcock Medical Center
Clyde Sullivan:
Echo Strain modeling. Advisor: Robert Palac, MD
Nicholas Skiadas:
Endothelial cell migration, and the effects of
different stent polymers have on
this.
Vijay Ramanath:
- Outcomes of Diabetics and Non-diabetics receiving bare metal stents versus drug eluting stents. Presented as poster and oral at CRT 2009 (included among the conferences “Ten Best” abstracts). Mentors: C. Thompson, J. Robb
- Defining the origin of Chronic Total Occlusions. Mentors: C. Thompson.
