ProDom is a protein domain family database constructed automatically by clustering homologous segments. The ProDom building procedure MKDOM2 is based on recursive PSI-BLAST searches [ALTS2]. The source protein sequences are non-fragmentary sequences derived from SWISS-PROT and TrEMBL databases. ProDom was first established in 1993 [SONN] and maintained by the Laboratoire de Gntique Cellulaire and the Laboratoire de Interactions Plantes-Microorganismes (INRA/CNRS) in Toulouse. It is now maintained by the PRABI (bioinformatics center of Rhone-Alpes). The ProDom database consists of domain family entries. Each entry provides a multiple sequence alignment of homologous domains and a family consensus sequence.
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Connect to: ProDom