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Evidence-Based Medicine (EBM) Resources

Evidence-Based Medicine is the integration of best research evidence with clinical expertise and patient values. [Sackett DL, Straus SE, Richardson WS, et al. Evidence-based medicine: how to practice and teach EBM. 2d ed. Edinburgh: Churchill Livingstone, 2000.]


Other Evidence Based Medicine Resources:



TRIP (Turning Research Into Practice) Database Plus
Simultaneously searches evidence-based sources of systematic reviews, practice guidelines, and critically-appraised topics and articles. Also searches MEDLINE’s Clinical Queries, medical image databases, e-textbooks, and patient information leaflets.



Filtered Resources [These appraise the quality of studies and often make recommendations for practice.]

  • Systematic Reviews and Meta-Analyses:

The Cochrane Database of Systematic Reviews, published by the International Cochrane Collaboration, consists of detailed, structured topic reviews of hundreds of articles. Teams of experts complete comprehensive literature reviews, evaluate the literature, and present summaries of the findings of the best studies.

The Database of Abstracts of Reviews of Effects (DARE) contains over 4000 abstracts of quality assessed and critically appraised systematic reviews. DARE is produced by the National Health Services' Centre for Reviews and Dissemination (NHS CRD) at the University of York in the UK. [Note: search DARE in the Cochrane Library; the results are listed as "Other Reviews".]

Systematic Reviews are also searchable in MEDLINE:

PubMed: Conduct your search and then use the "Article types" filter on the left to select "Systematic Reviews".

Ovid MEDLINE: Enter your search query. Click on the “Additional Limits” button; select “Systematic Reviews” under “Publication Types.”

  • Critically-Appraised Topics (Evidence Syntheses):

DynaMed
DynaMed™ is a clinical reference tool created by physicians for physicians and other health care professionals for use at the point-of-care. With clinically organized summaries for more than 3,200 topics, DynaMed provides the latest content and resources with validity, relevance and convenience, making DynaMed an excellent resource for answering clinical questions during practice.

National Guideline Clearinghouse
A comprehensive database of evidence-based clinical practice guidelines and related documents produced by the Agency for Health Care Research and Quality, in partnership with the American Medical Association and the American Association of Health Plans. Updated weekly. Note: guideline evidence varies from expert opinion to high levels of evidence.

  • Critically-Appraised Individual Articles (Article Synopses):

The ACP Journal Club is published by the American College of Physicians-American Society of Internal Medicine. The editors of this journal screen the top 100+ clinical journals and identify studies that are methodologically sound and clinically relevant. An enhanced abstract, with conclusions clearly stated, and a commentary are provided for each selected article.

Evidence Updates
From BMJ Publishing Group and McMaster University's Health Information Research Unit. Quality articles from over 110 clinical journals are selected by research staff, then rated for clinical relevance and interest by an international group of physicians. Includes a searchable database of the best evidence from the medical literature and an email alerting system.

Dartmouth EBM Database
The Evidence-Based Medicine database at Dartmouth-Hitchcock Medical Center is designed to provide rapid access to clinically important trials likely to be of use in the practice of medicine. It is maintained and updated by members of the Department of Medicine. Studies that are summarized have high quality and level of evidence (e.g., randomized control trial, meta-analysis, systematic review) and have been formatted to allow rapid retrieval.

“Evidence-Based…” Journal series
Search the Dartmouth eJournal collection for the title "Evidence-Based". Primary research articles within the discipline are selected for quality and clinical relevance. A structured abstract and expert commentary are provided for each study.



Unfiltered Resources [Finding an original study]

Evidence is not always available via filtered resources. It is possible to use specific search strategies in MEDLINE to achieve the highest possible level of evidence. Use critical appraisal worksheets to evaluate studies.

To limit your PubMed search to the best evidence-producing studies:

  • Click on "Clinical Queries" (under "PubMed Tools"). This specialized search is intended for clinicians and is your fastest way to conduct an evidence-based search for a research article. Pull-down menus allow search results to be filtered by your type of clinical question,  and to choose a more sensitive (Broad) or more specific (Narrow) search.
  • Alternately, conduct your search and then use the "Article types" filter on the left to select the type of study that offers the highest level of evidence given your specific clinical question.

To limit your Ovid MEDLINE search to the best evidence-producing studies:

  • Clinical Queries is searchable in Ovid; click on the "Additional Limits" button.

Background Information/Expert Opinion

  • UpToDate
    A clinical information resource which offers up-to-date, fully referenced expert answers to patient-care, diagnosis, and treatment questions. Topic reviews are written by recognized authorities who review the topic, synthesize the evidence, summarize key findings, and provide specific recommendations. (Access restrictions: Licensed for use by Dartmouth College/ DMS/ DHMC.)

  • eMedicine
    Physician authors and editors contribute to the eMedicine Clinical Knowledge Base, which contains articles on 7,000 diseases and disorders. The evidence-based content provides the latest practice guidelines in 62 medical specialties. eMedicine's professional content undergoes multiple levels of physician peer review.

  • eBooks
    Full-text electronic books.

  • National Guideline Clearinghouse
    A comprehensive database of evidence-based clinical practice guidelines and related documents produced by the Agency for Health Care Research and Quality, in partnership with the American Medical Association and the American Association of Health Plans. Updated weekly. Note: guideline evidence varies from expert opinion to high levels of evidence.


EBM Information Sites


EBM Tutorials