| On Doctoring MEDLINE searches, with reference librarian comments |
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The question was
"What is the therapeutic use, physiology and
pharmacokinetics of LDL?"1 : Lipoproteins, hdl/tu [Therapeutic Use] {11}
2 : Lipoproteins, hdl/pk [Pharmacokinetics] {23}
3 : Lipoproteins, hdl/ph [Physiology] {97}
4 : from 3 keep 17,45 {2}
5 : from 1 keep 2-3,10 {3}
6 : 4 or 5 {5}
7 : from 6 keep 1-5 {5}
8 : from 6 keep 1-5 {5}
Reference Librarian comments
I was a little confused as to whether you meant HDL or LDL, but I
think that got cleared up in a separate message. My advice with this
search strategy would be to "explode" the term lipoproteins, so that
you get...LIPOPROTEINS, HDL CHOLESTEROL
SCOPE: Cholesterol which is contained in or bound to high density
lipoproteins (HDL). High density lipoproteins transport cholesterol from
peripheral tissues to the liver thereby acting as a scavenger to prevent
excess accumulation and deposition of cholesterol in blood vessels.... which I think you'd want. I think you could safely check the
"Focus" box too, so as to get really "on-target" references. Doing
it in three separate sets is just fine and dandy. Sometimes it's
nice to have things separate. But just for your info -- you could
get all three sub-headings (aspects) in one fell swoop.In other words, you could do this:
exp *lipoproteins, hdl/tu,pd,ph -- and you'd get 202
...and then limit to human and english and get 121
...and then take it from there.
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