On Doctoring MEDLINE searches, with reference librarian comments

The question was

"p53 expression as aprognostic indicator after
radical prosectomy"

1 :  *Genes, p53/ or *Protein p53/         {7004}
2 :  Randomized controlled trials/         {10813}
3 :  Prostatectomy/         {3808}
4 :  1 and 3         {10}
5 :  from 4 keep 2,6,9         {3}
6 :  from 4 keep 2,6,9         {3}
7 :  from 6 keep 1-3          {3}

Reference Librarian comments

Fine job. Remember to "explode" the MeSH terms whenever possible. I
played around with the search myself, and found it to be a little
tricky. "Prognosis" is not easy & direct to search for in MEDLINE.

Here's what I did, which is not "better," just different...

1 : 
exp genes, p53/
{5129}

2 : 
exp protein, p53/
{6314}

3 : 
exp prostatic neoplasms/
{13913}

4 : 
3 and (1 or 2)
{184}

5 : 
limit 4 to (human and english language)
{169} 16