Optics in Medicine Blog

Fluorescence Tomography

Molecular Therapy has the potential to improve the prognosis for difficult to treat cancer types, including glioblastoma multiform and pancreatic cancer. By targeting tumors, this non-invasive form of treatment delivers drugs directly to cancerous cells without damaging healthy tissue. Currently, this approach to molecular imaging is being tested at the Dartmouth Hitchcock Medical Center (DHMC). [...]

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Combining NIRST and BTS

While screen-film mammography has been proven to reduce the mortality of the disease, the screening method has its limitations. As Professor Keith Paulsen explains in this video published by the Thayer School of Engineering, doctors often find the images created by mammography difficult to read due to “tissue overlap”—a type of distortion that occurs when [...]

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DCCNE Featured in NH Magazine

On Monday, October 1st, the cancer research conducted by the Dartmouth Center for Cancer Nanotechnology Excellence (DCCNE) was featured on the website of NH Magazine. The article explains a number of non-invasive cancer treatment approaches, including targeted drug delivery. DCCNE is funded by $12.8 million grant from the National Cancer Institute (NCI). Each year, members [...]

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Photo featured on OSA’s web page!

Titled Long Exposure Image, PhD student Adam Glaser describes describes the piece as: “Long exposure image of Čerenkov radiation and the induced fluorescence from a dilute amount of Fluorescein in water when irradiated with a medical LINAC megavoltage electron beam.” Check out the photo on the OSA’s website, and be sure to comment and share! [...]

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Prototype Testing in China

Located on the second floor of the Dartmouth Hitchcock Medical Center (DHMC), the Advanced Imaging Center houses several imaging devices used by the Optics in Medicine Laboratory. Currently, graduate student Michael Mastanduno is testing a prototype that combines Magnetic Resonance Imaging (MRI) with Optical Tomography into a singular imaging device. This has the potential to [...]

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Tomographic Imaging

Tomographic imaging creates three-dimensional models of breast cancer that supplement the information provided by mammograms, a breast cancer screening method commonly used in hospitals. Currently, the Optics in Medicine Laboratory is researching a number of methods to improve these imaging techniques, and is developing medical devices that integrate tomographic imaging with other tumor-modeling techniques. This July, [...]

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First-Year Student, Yan Zhao

The Optics and Medicine Laboratory would like to welcome its newest graduate student, Yan Zhao, to Hanover. Originally from Xuchang, China, Yan received his bachelors degree in engineering from Xian Jiaotong University. While at Jiaotong, Yan published a paper titled “Polarization dressings of four-wave mixing process in a V-type three-level atomic system” in Optics Communications. [...]

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CIHR Fellow: Kenneth Tichauer

Kenneth Tichauer, a third-year Research Associate in the Optics in Medicine Laboratory, was awarded a Postdoctoral Fellowship by the Canadian Institutes of Health Research (CIHR) during the 2011-12 academic year. Ken’s research project, Imaging HER2 receptor binding in breast during the course of therapy with dual-agent fluorescence, was ranked 3rd out of the 400 applicants [...]

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Epithelial and Stromal Imaging

Scattered light measured from tissue can be uniquely correlated to tissue substructure, function and progression of disease. The ultrastructural information provided by scatter may render optical techniques valuable to diagnosis. Many recent studies have demonstrated that scattered light measured from tissue can be uniquely correlated to tissue substructure, function and progression of disease, if the [...]

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Image-guided NIR Spectroscopy

Image-guided NIR Spectroscopy

IG-NIRS provides deep tissue functional characterization at high resolution. This approach combines conventional imaging techniques such as MRI and CT with optical NIR technologies, giving information directly relating to the vascular and metabolic status of tissue in-vivo. Image-guided near infrared spectroscopy (IG-NIRS) provides deep tissue functional characterization at high resolution. This approach combines conventional imaging [...]

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