Čerenkov radiation in therapy

In the latest issue of Optics Letters, Dartmouth’s Optics in Medicine Laboratory published an article titled Čerenkov excited fluorescence tomography using external beam radiation. Conducted by graduate students Jennifer-Lynn Demers, Rongxiao Zhang, research scientist Scott Davis, lab director Brian Pogue, and Associate Professor of Medicine David Gladstone, the study examines the use of Čerenkov radiation in non-invasive cancer treatment. In this study, the lab examines a cancer treatment method that combines external beam radiation therapy (EBRT) with optical measurement of targeted fluorophore excited by Čerenkov radiation. In the study, optical measurements were taken from 13 locations on a tissue phantom to separate the fluorophore emissions from the Čerenkov continuum.