Our Students
Student Profiles
Ronald
C. Kaltreider
PhD
Publications during training:
Hamilton JW, Kaltreider
RC, Bajenova OV, Ihnat MA, McCaffrey J, Turpie BW, Rowell
EE, Oh J, Nemeth MJ, Pesce CA, and Lariviere JP. Molecular
basis for the effect of carcinogenic heavy metals on inducible
gene expression. Environ Health Perspect 106(S4): 1005-1015,
1998.
Hamilton JW, Kaltreider
RC, Davis AM, and Green RA. Arsenic(III) and chromium(VI)
alter glucocorticoid receptor (GR) function and GR-dependent
gene regulation. Metal Ions Bio Med 6:66-68, 2000.
Kaltreider RC, Bajenova
OV, Warren AJ, Mustra CJ, Ihnat MA, Pesce CA, Lariviere JP,
and Hamilton JW. Identification of specific transcription
factors and gene promoter regions mediating the preferential
effects of DNA crosslinking agents on inducible gene expression.
Proc Am Assoc Cancer Res 39:631, 1998.
Kaltreider RC, Davis
AM and Hamilton JW. Chromium(VI) indices a hormone-independent
activation of the glucocorticoid receptor. The Toxicologist
48:333, 1999.
Kaltreider RC, Davis
AM and Hamilton JW. Hormone-independent activation of the
glucocorticoid receptor by chromium(VI) in H4IIE cells. Proc
Am Assoc Cancer Res 40:504, 1999.
Kaltreider RC, Davis
A, Lariviere JP, and Hamilton JW. Arsenic alters the function
of the glucocorticoid receptor as a transcription factor.
Environ Health Prespect 109:245-251, 2001.
Kaltrieder RC, Ihnat
MA, Pesce CA, Nemeth MJ, Lariviere JP, and Hamilton JW. Arsenic
and chromium induce metal-, dose-, time-, and cell factor-dependent
alterations in transcription factor binding. The Toxicologist
36:116, 1997.
Kaltreider RC, Ihnat
MA, Andrew AS, Oh J, JP Lariviere, and JW Hamilton. Effects
of the heavy metals arsenic and chromium on transcription
factor biding and gene expression. The Toxicologist 42:321,
1998.
Kaltrieder RC, Pesce
CA, Ihnat MA, Lariviere JP, and Hamilton JW. Differential
effects of arsenic(III) and chromium(VI) on nuclear transcription
factor binding. Mol Carcinogen 25:219-229, 1999.
Kaltreider RC, Warren
AJ, Ihnat MA, Powell EE, and Hamilton JW. The DNA crosslinking
agents mitomycin C and chromium(VI) alter transcription factor
binding and gene expression. Proc Am Assoc Cancer Res 38:38,
1997.
Ihnat MA, Lariviere
JP, Kaltreider RC, Warren AJ, and Hamilton JW. Mitomycin C
suppression of multidrug resistance-associated protein expression
in human breast cancer/nude mouse xenografts in vitro. Proc
Am Assoc Cancer Res 38:481, 1997.
Ihant MA, Lariviere
JP, Warren AJ, Anthony SP, Kaltreider RC, and Hamilton JW.
Effects of mitomycin C and carboplatin on multidrug resistance-associated
protein expression and on subsequent suppression of tumor
growth by doxorubicin and paclitaxol in human metastatic breast
cancer xenografted nude mice. Oncol Res 11:303-310, 1999.
Warren AJ, Mustra DJ,
Ihnat MA, Anthony SP, Kaltreider RC, Lariviere JP and Hamilton
JW. Detection of mitomycin C-DNA adducts in the tumors of
human breast cancer patients and human metastatic breast cancer
xenografted nude mice by 32P-postlabeling. Proc Am Assoc Cancer
Res 39:631, 1998.
Awards and Presentations
during training:
1997, 1998 - Presentations at the NIEHS
national Superfund Meeting, North Carolina and Boston.
1997, 1998, 1999 -
Presentations at the annual Society of Toxicology meetings
and American Association for Cancer Research.
2000 - Strohbehn Award
for Outstanding Graduate Thesis, Dartmouth Medical School,
Hanover, NH. Thesis (Pharmacology and Toxicology): Characterization
of the Molecular Mechanism by which Arsenic and Chromium Alter
inducible Gene Expression.
Presentations at New England Pharmacology
meetings and the Nutmeg regional toxicology meetings.
Current position: Assistant professor,
York College of Pennsylvania.
