Andrew C. Vail Professor of Physiology
After graduating from Dartmouth College in 1959 with a B.A. in English, Dr. Bartlett attended medical school at Dartmouth and Harvard, receiving his M.D. in 1964. He studied physiology at Dartmouth as a predoctoral fellow in 1961-62. Following internship and residency training in internal medicine at Strong Memorial Hospital in Rochester, New York, he joined the U.S. Public Health Service, serving first as an air pollution epidemiologist and then as Chief of the Medical Research Section of the Health Effects Research Program at the National Center for Air Pollution Control. In 1968 he returned to Dartmouth as a postdoctoral fellow in Physiology and joined the faculty in 1971. He has been Professor of Physiology since 1978 and was named Andrew C. Vail Professor. He served as Department Chairman for 16 years from 1989–2005.
Dr. Bartlett's research is directed at elucidating the role of the upper airways in the control of breathing. Studies focus both on the sensory physiology of the upper respiratory tract and on the control of muscles that influence resistance to airflow through the nose, pharynx, larynx and trachea. Current projects focus on mechanisms of control and integration of breathing movements by muscles of the respiratory pump and those of the upper airway. Reflex responses to afferent stimuli from the carotid baroreceptors and upper airway chemo- and mechanoreceptors are being investigated. The work is intended to advance the understanding of normal upper airway physiology and to provide information that will aid in the diagnosis and management of diseases, such as obstructive sleep apnea and the sudden infant death syndrome.
Bartlett, D., Jr. and S.L. Knuth. Bladder contractions alter inspiratory termination by superior laryngeal and intercostal nerve stimulation. Respir. Physiol. 120:105-114, 1999
Stella, M.H., S.L. Knuth and D. Bartlett, Jr. Respiratory response to spontaneous contractions of the urinary bladder in awake and decerebrate rats. Respir. Physiol. 120:105-114, 2000.
Stella, M.H., S.L. Knuth and D. Bartlett, Jr. Respiratory response to baroreceptor stimulation and spontaneous contractions of the urinary bladder. Respir. Physiol. 124:169-178, 2001.
Stella, M.H., S. L. Knuth and D. Bartlett, Jr. Respiratory response to mechanical stimulation of the gallbladder. Respir. Physiol. & Neurobiol. 130: 285-292, 2002.
Bartlett, D., Jr. and S. L. Knuth. Influence of hypercapnia and hypocapnia on bladder contractions and their respiratory consequences. Respir. Physiol. & Neurobiol. 134: 247-253, 2003.
van der Velde, L., A. K. Curran, J. J. Filiano, R. A. Darnall, D. Bartlett, Jr. and J. C. Leiter. Prolongation of the laryngeal chemoreflex after inhibition of the rostral ventral medulla in piglets: a role in SIDS? J. Appl. Physiol. 94: 1883-1895, 2003.Curran, A.K., L. Xia, J.C. Leiter and D. Bartlett, Jr. Elevated body temperature ehances the laryngeal chemoreflex in decerebrate piglets. J. Appl. Physiol. 98: 780-86, 2005.
Xia, L., J.C. Leiter and D. Bartlett, Jr. Laryngeal Water receptors are insensitive
to body temperature in neonatal piglets. Respir. Physiol. & Neurobiol. 150: 82-86,
2006.Xia, L. T. Damon, J. C. Leiter and D. Bartlett, Jr. Focal warming in the nucleus of the solitary tract prolongs the laryngeal chemoreflex in decerebrate piglets. J. Appl. Physiol. 102:54-62, 2007.
Böhm I., L. Xia, J. C. Leiter and D. Bartlett, Jr. GABAergic processes mediate thermal prolongation of the laryngeal reflex apnea in decerebrate piglets. Respir. Physiol. & Neurobiol. 156:229-233, 2007.
Xia, L., T. Damon, M. M. Niblock, D. Bartlett, Jr. and J. C. Leiter. Unilateral microdialysis of gabazine in the dorsal medulla reverses thermal prolongation of the laryngeal chemoreflex in decerebrate piglets. J. Appl. Physiol. 102: 1864-1872, 2007.
Xia, L., J.C. Leiter and D. Bartlett, Jr. Laryngeal apnea in rat pups: effects of age and body temperature. J. Appl. Physiol. 104: 269-274, 2007.
Xia, L., D. Bartlett, Jr. and J. C. Leiter. An adenosine A2A antagonist injected in the NTS reverses thermal prolongation of the LCR in decerebrate piglets. Resp. Physiol. & Neurobiol., In press, 2008.
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