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Joshua
W. Hamilton Ph.D.
Director, Center for Environmental
Health Sciences at Dartmouth
Director, Toxic
Metals Research Program
Director, Dartmouth Molecular Biology Support Laboratory
Professor, Department of Pharmacology and Toxicology
Dartmouth Medical School
Professor
Department of Chemistry
Dartmouth College
Dartmouth Medical School
7650 Remsen, Room 514
Hanover, NH 03755-3835
USA
Tel: 603-650-1316
Fax: 603-650-1129
E-mail: Joshua.Hamilton@Dartmouth.Edu
Areas of Expertise:
Molecular toxicology
Specialties: Toxicology of metals;
Endocrine disruption; Chemical carcinogenesis
Research Topics/Working Groups:
Molecular toxicology of metals/ group leader; Endocrine disruption;
Molecular biomarkers; Epidemiology of arsenic; Epidemiology of
environmental agents in children; Toxic Metals Research Program/Director
Research: Joshua Hamilton investigates how environmental
chemicals, particularly toxic metals, affect biochemical processes
in ways that might contribute to human disease. More specifically,
he studies the preferential effects of the carcinogenic metals
arsenic and chromium on gene expression at very low doses. He
and his research group recently discovered that arsenic can act
as an endocrine disrupting chemical, and they are now focused
on whether these alterations in hormone-mediated pathways may
contribute to the ability of arsenic to increase the risk of diabetes,
vascular disease and certain cancers. |